Nitroimidazoline derivatives and preparation method thereof and application thereof
A technology for nitroimidazolidine derivatives, which is applied in the field of nitroimidazolidine derivatives and their preparation and application, can solve difficult problems such as treatment, and achieve high insecticidal activity and simple synthesis method
Inactive Publication Date: 2010-09-15
WUHAN INSTITUTE OF TECHNOLOGY
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In addition, because imidacloprid contains a large amount of pollutants in the production process of pyridine ring, it is difficult to control
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Abstract
The invention relates to nitroimidazoline derivatives. The nitroimidazoline derivatives have a structural formula shown in a formula I, wherein R is substituted benzene, naphthalene, benzoxazole or benzimidazole. The preparation method comprises that different substituted chloromethylene compounds, N-nitroimidazoline, potassium carbonate and solvent are reacted to form the nitroimidazoline derivatives. The nitroimidazoline derivatives have the advantages that: 1) the synthetic method for the nitroimidazoline derivative compounds is simple; and 2) the nitroimidazoline derivative compounds have a structure different from that of imidacloprid and have high insecticidal activity, the structure of the compounds does not comprise pyridine rings, and the compounds have wide development prospect.
Description
technical field The present invention relates to nitroimidazolidine derivatives and their preparation methods and applications. Background technique Neonicotinoid insecticides, especially imidacloprid, have made great contributions to the control of piercing-sucking aphids, planthoppers, and leafhoppers since they were put on the market in 1991. The development of insecticides that act on nicotinic acetyl receptors is still Has great potential. It can be said that there is currently no crop that does not use imidacloprid, especially the two major crops of rice and vegetables, which are used at least twice a season, effectively solving the long-standing problems of piercing-sucking aphids, planthoppers, and leafhoppers. prevention issues. Imidacloprid is a new type of nitroimine insecticide. Its insecticidal mechanism is mainly a nicotinic acetylcholine receptor agonist in the insect nervous system, thereby blocking the normal conduction of the insect central nervous system...
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IPC IPC(8): C07D233/52C07D413/06C07D403/06A01N51/00A01P7/04
Inventor 巨修练刘根炎卢伦
Owner WUHAN INSTITUTE OF TECHNOLOGY
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