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Compound andrographis paniculata injection for treating pig hyperpyrexia and preparation method thereof

A technology of compound andrographis paniculata and injection, which is applied in the directions of medical preparations, antipyretics, and pharmaceutical formulations containing active ingredients, can solve the problems of treatment failure, inaccurate pathogens, poor treatment effects, etc. simple effect

Inactive Publication Date: 2010-11-03
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is no specific medicine for the treatment of high fever in pigs, and some antibiotics are often used in clinical treatment, but the treatment effect is not good, and because the pathogen causing the infection cannot be determined, the treatment often fails, which brings great losses to the pig industry

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] (1) Weigh 50kg of Andrographis paniculata, put it into 400kg of purified water and decoct, keep boiling for 90 minutes, and filter. Add 300kg of purified water to the filtered medicinal dregs, decoct for the second time, keep boiling for 90 minutes, and filter. The combined two decoctions were concentrated to 50 L, added 100 kg of 95% ethanol, stirred evenly, precipitated for 24 hours, filtered, and collected the filtrate. Recover the ethanol in the filtrate until the filtrate has no alcohol smell, then concentrate the filtrate after recovering ethanol to 30L.

[0020] (2) Bupleurum 150kg, garlic 80kg, pulverized, distilled with circulating steam, collected distillate 300L, the obtained distillate was carried out secondary distillation, collected secondary distilled distillate 100L, obtained secondary distilled The distillate was distilled for the third time, and 50 L of the distillate was collected, and then 0.5 kg of Tween-80 and 0.9 kg of sodium chloride were added ...

Embodiment 2

[0023] (1) Weigh 150kg of Andrographis paniculata and put it into 1200kg of purified water to decoct, keep boiling for 90 minutes, and filter. Add 900kg of purified water to the filtered medicinal residues, decoct for the second time, keep boiling for 90 minutes, and filter. Combine the two decoctions, concentrate to 50L, add 100kg of 95% ethanol, stir evenly, precipitate for 24 hours, and filter. Collect the filtrate, recover the ethanol in the filtrate until the filtrate has no alcohol smell, then concentrate the filtrate after recovering the ethanol to 30L.

[0024] (2) Bupleurum 50kg, garlic 30kg, pulverized, distilled with circulating steam, collected distillate 300L, the obtained distillate was carried out secondary distillation, collected secondary distilled distillate 100L, obtained secondary distillation The distillate was distilled for the third time, and 50 L of the distillate was collected, and then 0.5 kg of Tween-80 and 0.9 kg of sodium chloride were added to th...

Embodiment 3

[0027] (1) Weigh 80 kg of Andrographis paniculata, put it into 640 kg of purified water and decoct, keep boiling for 90 minutes, and filter. Add 480kg of purified water to the filtered medicinal dregs, decoct for the second time, keep boiling for 90 minutes, and filter. Combine the two decoctions, concentrate to 50L, add 100kg of 95% ethanol, stir evenly, precipitate for 24 hours, and filter. Collect the filtrate, recover the ethanol in the filtrate until the filtrate has no alcohol smell, then concentrate the filtrate after recovering the ethanol to 30L.

[0028] (2) Bupleurum 120kg, garlic 70kg, pulverized, distilled with circulating steam, collected distillate 300L, the obtained distillate was carried out secondary distillation, collected secondary distilled distillate 100L, obtained secondary distillation The distillate was distilled for the third time, and 50 L of the distillate was collected, and then 0.5 kg of Tween-80 and 0.9 kg of sodium chloride were added to the th...

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PUM

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Abstract

The invention discloses compound creat injection used for treating hyperpyrexia of a pig and a preparation method thereof, aiming to provide the compound creat injection for treating the hyperpyrexia of the pig with small side effect and the preparation method thereof with the advantages of simple technique and easy realization. Each 100 liters of the injection is prepared by the following raw materials: 50 to 150 kilograms of creat, 0.5 to 5 kilograms of zedoary turmeric oil, 50 to 150 kilograms of Chinese thorowax, 30 to 80 kilograms of garlic, 0.5 kilograms of tween-80, 0.9 kilograms of sodium chloride, 100 kilograms of 95 percent ethanol, the balance being injection water. The compound creat injection is formed by the creat and three traditional Chinese medicines including the Chinesethorowax , the zedoary turmeric oil and the garlic, has the efficacies of antivirus, antibacteria, fever reduction and improvement of the immunity of an organism through reasonable determination of the content of various compositions, strengthens intrinsic phagocytic function, is effective to drug-resistant pathogen of western medicines and the hyperpyrexia of the pig, and relieves the stress reaction of the pig. Simultaneously, the product is traditional Chinese medicine preparation, has small side effect, does not aggravate the burden of the liver and the kidney, and can effectively treat an illness.

Description

technical field [0001] The invention relates to a compound Andrographis paniculata injection for treating hyperthermia in pigs and a preparation method thereof. Background technique [0002] Pig hyperthermia is a disease that appears now. The main cause of this disease is the mixed infection of bacteria and viruses. There are many kinds of bacteria and viruses that cause infection. Fever, high fever, red and blue skin, extremely low body resistance, lack of energy, loss of appetite, and high mortality rate of sick pigs. [0003] At present, there is no specific medicine for treating hyperthermia in pigs. Clinically, some antibiotics are often used for treatment, but the treatment effect is not good, and because the pathogen causing the infection cannot be determined, the treatment often fails, which brings great losses to the pig industry. Contents of the invention [0004] The present invention aims to overcome the deficiencies in the prior art, and can provide a compoun...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/906A61P29/00A61P31/04A61P31/12
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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