Preparation of shaolin plaster for rheumatism and wound and quality control method

Abstract

The invention relates to a preparation and quality control method of a Shaolin rheumatism trauma paste. The original production process of the Shaolin rheumatism trauma paste has the problems that (1) power consumption of plastication is great; (2) temperature rises quickly in the plastication, which results in easy aging and loss of cohesive force; (3) the menthol, menthyl salicylate and borneol in the prescription are once tried for soaking rubber to carry out the plastication, which leads to excessive loss of the components in finished products; when petrolatum is used for replacing the components to soak the rubber for carrying out the plastication, serious problem of oil permeation occurs in the finished products; (4) the relative density of the extract of medical material specified by the standards can not be controlled. The invention aims at providing the preparation and quality control method of the Shaolin rheumatism trauma paste, proposing a reasonable prescription of base materials and a production technique to ensure that finished products have clean and smooth appearance and good cohesive force and reducing the loss of active components of the finished products, particularly the volatile components such as menthol, menthyl salicylate and borneol. The quality standards essentially comprises thin layer identification of angelica, forsythia fruit, rhubarb root, root of common peony and resina draconis, limit tests on adhesion ability and aconitine and determination of the content of menthol, menthyl salicylate and borneol of the products by gas chromatography.

Description

technical field [0001] The invention relates to a preparation and quality control method of medicine, in particular to a preparation and quality control method of Shaolin Fengshi Dieda Ointment. Background technique [0002] Rubber plaster is a modern preparation, including two types of drug-containing and drug-free (adhesive plaster). The rubber plaster has strong adhesion, is easy to use and carry, can be pasted directly on the affected area without preheating and softening, does not pollute the clothes, and has almost no damage to the body; but because the plaster is thin and the drug load is limited, the extraction of drugs or medicinal materials should be controlled as much as possible amount of things. The preparation methods include ① solvent method: first extract the drug, then immerse the treated raw rubber in gasoline, swell it into a glue, then add tackifier, softener, filler, etc. to make a matrix, and then add medicinal materials The extract is mixed well to f...

AI Technical Summary

Problems solved by technology

The advantages are aging resistance, strong performance, and good design performance. The disadvantage is that the stickiness is not as good as that of rubber plasters.

The solvent method can easily lead to the loss of volatile components. Now most of them are produced by hot pressing method. The Shaolin Fengshi Dieda Ointment recorded in the 2005 edition of the original "Chinese Pharmacopoeia" by Anyang Zhongzhi Pharmaceutical Co., Ltd. has (1) The power consumption of mastication is large; (2) The temperature of mastication rises quickly, and it is easy to lose its cohesive force due to aging; (3) It has been tried to soak rubber mastication with menthol, methyl salicylate, and borneol in the prescription, and the finished product is as above If the loss of components is too large, if vaseline is used to soak rubber for plastication, the problem of oil penetration of the finished product will be serious. (4) The relative density of the medicinal material extraction extract specified in the standard cannot be controlled, etc.

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