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Pharmaceutical combination with depression resistance and angst resistance effect and method of preparing the same

A composition and anti-anxiety technology, which is applied in the direction of drug combination, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve the problems of obvious side effects, high price, no effect, anti-depression, anti-anxiety Chinese patent medicines, etc.

Inactive Publication Date: 2008-09-03
SHENZHEN TONIC MEDICINE TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the chemical drugs for the treatment of such diseases generally have disadvantages such as many adverse reactions, obvious side effects, and high prices, patients often refuse to take them.
Traditional Chinese medicine has a certain effect on the above diseases, but there is no Chinese patent medicine with definite effect on anti-depression and anti-anxiety

Method used

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  • Pharmaceutical combination with depression resistance and angst resistance effect and method of preparing the same
  • Pharmaceutical combination with depression resistance and angst resistance effect and method of preparing the same
  • Pharmaceutical combination with depression resistance and angst resistance effect and method of preparing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0195] [Example 1] Preparation of granules of the pharmaceutical composition of the present invention

[0196] Weigh 10g of Bupleurum, 10g of Gardenia, 10g of Angelica, 10g of Rhizoma Cyperi, 5g of Coptidis, 10g of Pinellia, 10g of Schisandra, and 10g of Codonopsis, and set aside.

[0197] Extract Angelica, Schisandra, Coptidis, Pinellia plus 8 times the amount of 70% ethanol for 3 times, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure, dry under reduced pressure below 60°C to obtain component 1.

[0198] Boil Bupleurum, Gardenia, Cyperus, and Dangshen 10 times in water for 3 times, each time for 1 hour, filter, combine the filtrates, concentrate to a relative density of 1.05-1.15 (70-85°C heat test), and let stand , filtered, the filtrate was concentrated and dried to obtain component 2; combined component 1 and component 2, pulverized into powder, mixed uniformly, and granulated to obtain the product.

Embodiment 2

[0199] [embodiment 2] tablet preparation of pharmaceutical composition of the present invention

[0200] Weigh Bupleurum 10g, Gardenia 10g, Chuanxiong 10g, Chenpi 6g, Schisandra 10g, Coptis 5g, Codonopsis 10g, Pinellia 10g, set aside

[0201] Extract Chuanxiong, Schisandra, Coptidis, and Pinellia with 8 times the amount of 70% ethanol for 3 times, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure, and dry under reduced pressure below 60°C to obtain component 1.

[0202] Boil Bupleurum, Gardenia, Tangerine Peel, and Dangshen in 10 times the amount of water for 3 times, each time for 1 hour, filter, combine the filtrate, concentrate to a relative density of 1.05-1.15 (70-85°C thermal test), let stand, Filtration, the filtrate was concentrated and dried to obtain component 2;

[0203] Combine component 1 and component 2, pulverize into powder, mix evenly, and press into tablets to obtain.

Embodiment 3

[0204] [embodiment 3] tablet preparation of pharmaceutical composition of the present invention

[0205] Weigh 10g of Bupleurum Radix, 10g of Cortex Moutan, and 10g of Rhizoma Chuanxiong, and set aside.

[0206] Ligusticum chuanxiong and Moutan cortex plus 8 times the amount of 70% ethanol were extracted 3 times, each time for 1 hour, filtered, the filtrates were combined, ethanol was recovered under reduced pressure, and dried under reduced pressure below 60°C to obtain component 1.

[0207] Add Bupleurum 10 times the amount of water to decoct 3 times, each time for 1 hour, filter, combine the filtrates, concentrate to a relative density of 1.05-1.15 (70-85°C heat test), let stand, filter, concentrate the filtrate, and dry. Get component 2;

[0208] Combine component 1 and component 2, pulverize into powder, mix evenly, and press into tablets to obtain.

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PUM

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Abstract

The invention discloses a Chinese medicinal composition with the effects of antidepressant and anti-anxiety, and belongs to the field of Chinese traditional medicines. The Chinese medicinal composition comprises (by weight parts) radix bupleuri 6-15, cape jasmine fruit 5-15 or paeonia suffruticosa bark 5-20, and angelica sinensis 3-15 or ligusticum chuanxiong 3-15; and can be prepared into any conventional oral preparations. Different ministerial drugs and adjuvant drugs are added according to different subjects to better exert therapeutic effect. The inventive composition has the effects of antidepressant and anti-anxiety; and can be used for relieving depression and anxiety with the advantages of definite therapeutic effect and rapid drug effect. The inventive composition can also be used for relieving headache, palpitation, insomnia and melancholia.

Description

[technical field] [0001] The invention relates to a pharmaceutical composition with antidepressant and anti-anxiety effects and a preparation method thereof, belonging to the field of traditional Chinese medicine. [Background technique] [0002] With the development of human beings and the progress of society, people's work and life style are constantly changing, social competition is intensifying, and physical activity is getting less and less. Therefore, depression and anxiety have become frequent health problems that plague people. Because the chemical drugs for the treatment of such diseases generally have many adverse reactions, obvious side effects, and high prices, patients often refuse to take them. Traditional Chinese medicine has certain curative effect in treating the above-mentioned diseases, but there is no definite antidepressant and anti-anxiety Chinese patent medicine at present. Therefore, it is urgently desired to have a medicine for effectively treating a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61P25/22A61P25/24
CPCA61K36/744A61K36/232A61K36/233A61K36/344A61K36/65A61K36/718A61K36/752A61K36/79A61K36/8888A61K36/8905A61P25/22A61P25/24A61K2300/00
Inventor (发明人请求不公开姓名)
Owner SHENZHEN TONIC MEDICINE TECH
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