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Traditional Chinese medicine preparation for preventing and controlling osteoporosis and method of preparing the same

A technology of osteoporosis and traditional Chinese medicine preparations, applied in the field of medicine, can solve the problems of uncertain long-term curative effect, high price, and many side effects, and achieve the effects of high activity retention rate of raw materials, simple composition, and long-term application safety

Inactive Publication Date: 2010-06-23
MACAU UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine (OP) mostly has the disadvantages of many side effects, high price, uncertain long-term efficacy, etc.

Method used

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  • Traditional Chinese medicine preparation for preventing and controlling osteoporosis and method of preparing the same
  • Traditional Chinese medicine preparation for preventing and controlling osteoporosis and method of preparing the same
  • Traditional Chinese medicine preparation for preventing and controlling osteoporosis and method of preparing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 1. Raw material weight ratio of active ingredients:

[0018] Psoralen 250g Epimedium 240g Rehmannia glutinosa 300g Salvia miltiorrhiza 260g Oyster 400g

[0019] 2. Preparation method

[0020] For the above five raw materials, add 60% ethanol to soak for 40 minutes, heat and reflux twice, each time for 1 hour, filter, combine the filtrate, recover the ethanol and concentrate to a density of about 1.3-1.5, then add an appropriate amount of starch to dry, crush, Get dry ointment powder for later use. The filtered medicinal dregs are decocted with water for 1 hour, the decoction is filtered, the filtrate is concentrated to a relative density of about 1.3-1.5, an appropriate amount of starch is added to dry, crushed to obtain a dry cream powder, and set aside. Mix the above-mentioned dry cream powder, crush it into fine powder, add appropriate amount of micro-powdered silica gel, mix evenly, pass through a 150 μm ± 6.6 μm sieve, put it into capsules, and make 1000 capsules...

Embodiment 2

[0023] 1. Raw material weight ratio of active ingredients

[0024] Psoralen 200g Epimedium 180g Rehmannia glutinosa 246g Salvia miltiorrhiza 200g Oyster 350g

[0025] 2. Preparation method

[0026] For the above five raw materials, add 80% ethanol to soak for 35 minutes, heat and reflux twice, each time for 1 hour, filter, combine the filtrate, recover the ethanol and concentrate it to a density of about 1.3-1.5, then add an appropriate amount of starch to dry, and dry it. Cream powder, spare. The dregs are decocted with water for 1 hour, the decoction is filtered, and the filtrate is concentrated to a relative density of about 1.3-1.5, and an appropriate amount of starch is added to dry it to obtain a dry cream powder for later use. The above dry cream powder is mixed, crushed into fine powder, sieved through a 150μm±6.6μm sieve, added with an appropriate amount of magnesium stearate, pressed into tablets to make 1000 tablets, coated, and obtained.

[0027] 3. Product char...

Embodiment 3

[0029] 1. Formula dosage

[0030] Psoralen 165g Epimedium 150g Rehmannia glutinosa 216g Salvia miltiorrhiza 150g Oyster 300g

[0031] 2. Preparation process

[0032] The above five raw materials are soaked in 95% ethanol for 25 minutes, then heated and refluxed twice, each time for 1 hour, filtered, combined with the filtrate, recovered ethanol and concentrated to a density of about 1.3-1.5, then added an appropriate amount of starch to dry, crushed, Get dry ointment powder for later use. The dregs are decocted with water for 1 hour, the decoction is filtered, the filtrate is concentrated to a relative density of about 1.3-1.5, an appropriate amount of starch is added, dried, crushed, and a dry cream powder is obtained. The above dry cream powder is mixed evenly, crushed into fine powder, made into soft material, granulated, granulated, sieved, made into 1000 granules, and then packaged.

[0033] 3. Product characteristics This product is brown to tan granules, with a fragr...

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Abstract

The present invention discloses a Chinese medicine for preventing and curing osteoporosis. The share by weight of the effective ingredients is respectively 12-48 shares by weight of malaytea scurfpea, 12-48 shares by weight of epimedium herb,18-48 shares by weight of prepared rehmannia root, 12-48 shares by weight of danshen root and 5-58 shares by weight of oyster. According to different characteristics of each Chinese herbal medicine, the ingredients are made into tablets, capsules, pills and granules by ethanol extraction, hot-water extraction and grinding. Animal experiments and the clinical observation show that the present invention has obvious function of invigorating the kidney and strengthening the bones, and obvious effect of prevention and cure for osteoporosis.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine preparation for preventing and treating osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis is a common and frequently-occurring disease in the elderly, and primary osteoporosis (OP) belongs to the category of "bone atrophy" in traditional Chinese medicine. The theory of traditional Chinese medicine believes that "the kidney is the innate foundation", "the kidney produces the bone marrow", and "it fills the bone". The strong growth and development of bones is closely related to the prosperity and decline of kidney essence. If kidney essence is sufficient, the marrow biochemistry will be active, and the bones will be nourished and strong. It is fundamentally recognized that deficiency of the kidney is the main pathogenesis of osteoporosis. Western medicine (OP) mostly has the disadvantages of many side effec...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61K9/16A61K9/20A61K9/48A61K47/12A61K47/02A61P19/10A61K35/56A61K35/618
Inventor 师晶丽吴伟康
Owner MACAU UNIV OF SCI & TECH
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