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Health food with efficacy for preventing osteoporosis and preparation method

A technology for health food and osteoporosis, applied in medical preparations containing active ingredients, active ingredients of phosphorus compounds, active ingredients of hydroxyl compounds, etc., can solve the problems of unreliable product safety, low absorption and utilization rate, etc. Calcium absorption and deposition, high absorption rate, no environmental pollution

Inactive Publication Date: 2007-12-26
上海多普富生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, calcium supplements in the market are mainly divided into three generations: the first generation is simply processed from animal bones, shells, pearls and compound calcium carbonate, etc.; the second generation of calcium supplements belongs to organic acid calcium, including calcium gluconate and acetic acid Calcium, calcium citrate, calcium malate, calcium lactate, etc. The main ingredient of the third-generation calcium supplement products is calcium L-threonate, which is a deep-processed product of vitamin C. All of them have low absorption and utilization rate and product safety. Sexual unreliability and other issues

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The weight purity is more than 98% stilbenol, the calcium phosphate tricalcium phosphate is more than 37.5% by weight, and the international unit is 100,000 IU of cholecalciferol, according to the weight ratio:

[0022] 1.5:98:0.5 Mix well and make capsules, the calcium content in each capsule is above 70mg.

[0023] Implementation Effect:

[0024] Feed the mice with the mixture in the capsules, the recommended dose for the human body is 1.2g / 60kg body weight per day, and the test set up three dose groups: low, medium and high doses: 0.1g, 0.2g, 0.6g / kg for each group, which is equivalent to the recommended dose for the human body 5 times, 10 times, 30 times the dose. At the same time, a blank control group was established. The femur weight, expansion strength, and bone density indicators of mice were tested. The test results showed that it can effectively prevent osteoporosis and improve bone strength.

[0025] The result is as follows:

[0026] group

...

Embodiment 2

[0030] Thoroughly mix stilbinol with a weight purity of more than 98%, tricalcium phosphate with a calcium weight content of more than 37.5%, and cholecalciferol with an international unit of 100,000 IU according to a ratio of 4.5:95:0.1 to prepare Capsules, the content of calcium in each capsule is more than 70mg.

[0031] Implementation effect: Feed the mice with the mixture in the capsule, the recommended amount for the human body is 1.2g / 60kg body weight per day, and the test set up three dose groups: low, medium and high doses: each group was 0.1g, 0.2g, 0.6g / kg respectively, equivalent to 5 times, 10 times, and 30 times the recommended dose for the human body. At the same time, a blank control group was established. The femur weight, expansion strength, and bone density indicators of mice were tested. The test results showed that it can effectively prevent osteoporosis and improve bone strength.

[0032] The result is as follows:

[0033] group

number ...

Embodiment 3

[0037] Thoroughly mix stilbinol with a weight purity of more than 98%, tricalcium phosphate with a calcium weight content of more than 37.5%, and cholecalciferol with an international unit of 100,000 IU according to a ratio of 3:96.5:0.5 to prepare Capsules, the content of calcium in each capsule is more than 70mg.

[0038] Implementation effect: Feed the mice with the mixture in the capsule, the recommended amount for the human body is 1.2g / 60kg body weight per day, and the test set up three dose groups: low, medium and high doses: each group was 0.1g, 0.2g, 0.6g / kg respectively, equivalent to 5 times, 10 times, and 30 times the recommended dose for the human body. At the same time, a blank control group was established. The femur weight, expansion strength, and bone density indicators of mice were tested. The test results showed that it can effectively prevent osteoporosis and improve bone strength.

[0039] The result is as follows:

[0040] group

number ...

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Abstract

The present invention relates to a health-care food with function capable of preventing osteoporosis and its preparation method. Its composition includes 95-98% of tricalcium phosphate, 1.5-4.5% of astragalus triphenol and 1-5per mill of cholecalciferol. Besides, said invention also provides the concrete steps of its preparation method.

Description

technical field [0001] The invention relates to a health food with the effect of preventing osteoporosis and a preparation method thereof, in particular to a health food containing polyphenol and polycalcium. Background technique [0002] Osteoporosis is a worldwide health problem that attracts more and more attention. At present, about 200 million people in the world suffer from osteoporosis, and its incidence rate has leapt to the seventh among common diseases and frequently-occurring diseases. About 75 million people suffer from it in the United States, Europe and Japan, and in the United States and Europe, there are about 2.3 million patients with fractures caused by osteoporosis every year, and this medical cost is about 23 billion US dollars per year. It imposes a financial burden on the individual and causes pain and disability to the patient. [0003] According to the nutritional survey of the existing dietary structure in my country, the calcium intake of resident...

Claims

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Application Information

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IPC IPC(8): A61K33/42A61K9/48A61P19/10A61K31/05A61K31/593
Inventor 郑善强
Owner 上海多普富生物技术有限公司
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