Medicine composition for preventing and treating diabetes mellitus and its use
A compound and diabetes technology, which is applied in the field of drug compound for the prevention and treatment of type I diabetes, and the field of peptides for the treatment of type I diabetes, can solve the problems of no physiological regulation of blood sugar level, short expression time, and difficulty in repeating successful experiments. , to achieve the effect of controlling autoimmunity, promoting proliferation and function, and promoting improvement
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment Construction
[0040] In vivo experiments in animal models of diabetes : In vivo experiments were performed with 4-week-old female db / db model mice (BKS.Cg-m+ / +Leprdb, lot number 000642) from Jackson Laboratories (Bar Harbor, ME, USA) from Charles River Canada (Montreal, QC, Canada) C57BLKS / J mice and CD1 mice were used as controls. Female NOD mice were purchased from Taconic Farms (Germantown, NY). The rats tested were kept under the conditions of controlled light (12hs / 12hs), constant temperature, and no pathogenic bacteria, and sufficient food and drinking water suitable for rodents were provided. NOD mice were fed regular sterile Charles River #5075 chow. Daily injection of low doses of STZ (55mg / kg, i.p.) for 5 consecutive days induced insulin secretion-deficient diabetic mice.
[0041] diabetes diagnosis : The blood glucose level of the rats was tested with AccuSoft AdvantageTM testing instrument or blood glucose meter (Roche Diagnostics) every week. Diabetes is diagnosed when t...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com