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Huoxiang Zhengqi drop pill an dits preparation

A technology of Huoxiangzhengqi dripping pills and dripping pills, which is applied in the field of medicine and can solve problems such as not meeting the needs of industrialization, affecting the production of pharmaceutical preparations, and starch gelatinization

Active Publication Date: 2009-08-05
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. The active ingredients of raw materials Atractylodes atractylodis, Tangerine Peel, Magnolia officinalis, and Angelica dahurica are extracted by percolation. The extraction method has a long production cycle and consumes a large amount of ethanol, which is not suitable for industrialization needs
[0005] 2. Poria cocos and Dabupi are extracted separately with water, which is a waste of time and resources, which is not conducive to industrial production
[0006] 3. Pinellia contains a large amount of starch, and starch tends to gelatinize into paste or block during production, which seriously affects the production of pharmaceutical preparations

Method used

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  • Huoxiang Zhengqi drop pill an dits preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0108] (a) Take Atractylodes atractylodis 160g, tangerine peel 160g, Magnolia officinalis (made from ginger) 160g, Angelica dahurica 240g, Poria cocos 240g, Dabupi 240g, raw pinellia 160g, dried ginger 13.5g, licorice extract 20g, Huoxiang oil 1.6ml, perilla leaf oil 0.8ml for later use:

[0109] (b), Atractylodes atractylodes, tangerine peel, Angelica dahurica, Magnolia officinalis add 70% ethanol and reflux extract twice, each time 2 hours, combine extracts, filter, recover ethanol, set aside; One time for 2 hours, the second time for 1 hour, combine the decoction, filter, and concentrate the filtrate to an appropriate amount under reduced pressure, add licorice extract, mix well and set aside; soak the raw pinellia in cold water, change the water every 8 hours, soak until After the heart is penetrated, add another 13.5g of dried ginger, add water and decoct twice, the first time is 3 hours, the second time is 2 hours, combine the decoction, filter, the filtrate is concentra...

Embodiment 2

[0110] Embodiment 2: the preparation of Huoxiangzhengqi dripping pills

[0111] (a), take 80g of Atractylodes atractylodis, 80g of tangerine peel, 240g of Magnolia officinalis, 120g of Angelica dahurica, 360g of Poria cocos, 120g of Dabupi, 80g of raw pinellia, 10g of licorice extract, 0.8ml of patchouli oil, and 0.4ml of perilla leaf oil for later use;

[0112] (b), Atractylodes atractylodes, tangerine peel, Angelica dahurica, Magnolia officinalis add 40% ethanol and reflux extract twice, each time 3 hours, combine extracts, filter, recover ethanol, set aside; 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, combine the decoction, filter, concentrate the filtrate to an appropriate amount under reduced pressure, add licorice extract, mix well and set aside; soak the raw pinellia in cold water, every 10 hours Change the water once, soak until the heart is clear, add another 13.5g of dried ginger, add water to decoct twice, the first time is 3....

Embodiment 3

[0113] Embodiment 3: the preparation of Huoxiangzhengqi dripping pills

[0114] (a) Take 240g of Atractylodes atractylodis, 240g of tangerine peel, 80g of Magnolia officinalis, 120g of Angelica dahurica, 360g of Poria cocos, 360g of Dabupi, 240g of raw pinellia, 10g of licorice extract, 2.4ml of patchouli oil, and 0.5ml of perilla leaf oil for later use;

[0115] (b), Atractylodes atractylodes, tangerine peel, Angelica dahurica, Magnolia officinalis add 45% ethanol and reflux extract twice, each time 4 hours, combine extracts, filter, recover ethanol, set aside; 3.5 hours for the first time, 2 hours for the second time, 1 hour for the third time, combine the decoction, filter, concentrate the filtrate to an appropriate amount under reduced pressure, add licorice extract, mix well and set aside; soak the raw pinellia in cold water, every 9 hours Change the water once, soak until the heart is clear, add 16.5g of dried ginger, add water and decoct twice, the first time is 3 hours...

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Abstract

The invention relates to a preparation method of Huoxiangzhengqi dripping pills. Specifically, extracting Atractylodes atractylodis, dried tangerine peel, angelica dahurica and Magnolia officinalis with ethanol; decocting Poria cocos and Dabupi with water; raw Pinellia using water extraction and alcohol precipitation Extract and combine the extracts, add other active ingredients of medicines, and make drop pills. The present invention overcomes the disadvantages of long production cycle of traditional Huoxiang Zhengqi preparations, large consumption of ethanol, waste of time and resources, and starch gelatinization of Pinellia fragrans is prone to sticky or lumpy phenomenon during production, which is not suitable for industrialization needs.

Description

technical field [0001] The invention relates to the field of medicine, in particular to Huoxiangzhengqi dripping pills and a preparation method thereof. Background technique [0002] The prescription of Huoxiang Zhengqi comes from Huoxiang Zhengqi Powder contained in "Taiping Huimin Hejiju Prescription Volume 2". Tangerine peel, bellflower, licorice. It has the effect of resolving the exterior, harmonizing the middle, and aromatizing the turbidity. It is mainly used for exogenous wind-cold, internal stagnation of dampness or feeling of heat-dampness, external symptoms such as cold and heat headache, internal chest and abdomen fullness, nausea, nausea, abdominal pain and diarrhea , greasy moss in the mouth, moist and slow pulse and other signs of damp resistance. This prescription is often used for those with the above syndromes such as gastrointestinal cold, acute gastroenteritis or indigestion. In addition, the use of this prescription in the treatment of febrile epidemi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/889A61K36/8888A61K36/752A61K36/575A61K36/535A61K36/53A61K36/484A61K36/284A61K36/232A61K36/076A61K9/20A61P1/12A61P29/00
Inventor 章顺楠刘顺航徐波董莉娜
Owner TIANJIN TASLY PHARMA CO LTD
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