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Medicine composition for improving cognitive function of senile organism

A technology for cognitive function and composition, which can be used in drug combinations, plant raw materials, organic active ingredients, etc., and can solve problems such as expensive safety, toxicology, and toxic and side effects

Inactive Publication Date: 2009-03-11
INST OF HYGIENE & ENVIRONMENTAL MEDICINE PLA ACAD OF MILITARY MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above drugs all have different degrees of toxic and side effects. If they are used as preventive drugs for elderly cognitive decline for a long time, there are still problems of high price and safety and toxicity.

Method used

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  • Medicine composition for improving cognitive function of senile organism
  • Medicine composition for improving cognitive function of senile organism
  • Medicine composition for improving cognitive function of senile organism

Examples

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Comparison scheme
Effect test

Embodiment 1

[0031] A composition for improving the cognitive function of an aging body, comprising: 1000 parts of blueberry extract, 120 parts of ginkgo leaf extract, vitamin B 6 20 servings, vitamin B 12 0.02 parts. The composition is made into tablets according to conventional methods, and can also be made into infusions, or capsules, or other oral dosage forms such as powders and the like.

[0032] Pharmaceutically acceptable auxiliary materials can also be added to make tablets, electuary or capsules according to conventional methods.

Embodiment 2

[0034] A composition for improving the cognitive function of an aging body, comprising by weight: 500 parts of blueberry extract, 60 parts of ginkgo leaf extract, vitamin B 6 10 servings, vitamin B 12 0.01 part. The composition is made into tablets according to conventional methods, and can also be made into infusions, or capsules, or other oral dosage forms such as powders and the like.

[0035]Pharmaceutically acceptable auxiliary materials can also be added to make tablets, electuary or capsules according to conventional methods.

Embodiment 3

[0037] A composition for improving the cognitive function of an aging body, comprising: 1500 parts of blueberry extract, 180 parts of ginkgo leaf extract, vitamin B 6 30 servings, vitamin B 12 0.03 parts. The composition is made into tablets according to conventional methods, and can also be made into infusions, or capsules, or other oral dosage forms such as powders and the like.

[0038] Pharmaceutically acceptable auxiliary materials can also be added to make tablets, electuary or capsules according to conventional methods.

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Abstract

The medicine composition for improving cognitive function of senile organism includes blue berry extract 500-1500 weight portions, gingko leaf extract 60-180 weight portions, vitamin B6 10-30 weight portions, and vitamin B12 0.01-0.03 weight portions. Animal experiment shows that the medicine composition of the present invention can raise the motion success of senile rat in a water labyrinth, inhibit the AChE activity in serum and hippocampal tissue, increase the conten of neurotransmitter, increase the vitamin E concentration in serum, strengthen the antioxidant capacity of serum and the activity of glutathione peroxidase and increase the group peak potential amplitude of hippocampal CA1 region. All these shows that the medicine composition is favorable to forming long term reinforced LTP and improve the cognitive function of senile rat.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a composition for improving the cognitive function of an aging body. Background technique [0002] With the development of social economy and scientific and technological progress, the life expectancy of human beings is continuously extended, and the trend of aging of the world population is becoming more and more obvious. Statistics show that there will be 590 million elderly people in the world in 2010, and it will increase to 1.1 billion in 2025. The elderly over 60 years old in my country are about 100 million at present, and will reach 280 million in 2025, accounting for 19.3% of the total population. At the same time, the incidence of cognitive decline in the elderly and neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease is also increasing year by year, which not only seriously affects the quality of life of the elderly, but also brings a heavy bu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/82A61K36/45A61K36/16A61K31/714A61K31/4415A61K31/375A61K31/355A61K31/519A61K31/202A61K31/352A61K31/191A61P39/06
Inventor 蒋与刚房恒通庞伟房红芸
Owner INST OF HYGIENE & ENVIRONMENTAL MEDICINE PLA ACAD OF MILITARY MEDICAL
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