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Soluble slow release external applied contraceptive

A contraceptive, soluble technology, applied in the field of medicine and health, can solve the problems of not being placed deep in the vagina, easy to stick, deformed, sticking to fingers, etc., and achieve the effects of prolonging the action time, simple production and stable effect.

Inactive Publication Date: 2009-02-25
高章圈
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently accepted dosage form is mainly nonoxynol film, which is prepared from polyethylene glycol as a matrix. Although the cost is low and the preparation method is simple, it is not completely satisfactory in use, such as: Since the film is thin and easily becomes sticky and deformed when exposed to water, it is required to pull out the finger quickly when placing it, otherwise the film will stick to the finger after encountering the vaginal fluid, and cannot be placed deep in the vagina, resulting in insufficient dosage. cause contraceptive failure

Method used

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  • Soluble slow release external applied contraceptive
  • Soluble slow release external applied contraceptive
  • Soluble slow release external applied contraceptive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: take by weighing nonoxynol ether 1.5kg earlier, degree of deacetylation is 92% water-soluble chitosan 15kg, glycerol (glycerol) 15kg, then each component that takes by weighing is mixed at normal temperature Add 375kg of distilled water, stir, pour into the mold after dissolving, and make a circular or semi-elliptical shell containing 30-100 mg of nonoxynol each, that is, a cap-shaped contraceptive film for external use, and then dry and remove the film , packaging, and finished products.

[0032] Other embodiment each component and consumption thereof are different from embodiment 1 and see the table below:

[0033]

[0034]

[0035] Appropriately increasing the proportion of plasticizer and film-forming agent in the formula of the present invention can enhance the water content and flexibility of the contraceptive of the present invention; increasing the proportion of chitosan can strengthen the hardness of the product of the present invention, but...

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PUM

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Abstract

The invention discloses an externally-applied soluble slow release contraceptive, which comprises nonoxynol 1.2-2.0 parts, chitosan 10-20 parts, humectant 5-20 parts and water 200-500 parts. The medicament can be released continuously.

Description

technical field [0001] The invention relates to medical hygiene, in particular to a contraceptive for external use. Background technique [0002] The implementation of the basic national policy of family planning has continuously played an important and positive role in improving the quality of our population, improving the level of reproductive health, and improving the overall strength of the nation. In this context, the research and development of related birth control technology and related contraceptives have developed rapidly, and various contraceptives have been launched one after another. For example, the common physical barrier contraceptives for women include vaginal diaphragms and contraceptive cervical caps. Before use, a gynecological examination is required. According to the size of the vagina, an appropriate type of vaginal diaphragm should be selected for trial insertion, and then learn how to put it in and out under the guidance of a doctor until you can ful...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/085A61K47/36A61K9/70A61P15/18
Inventor 高章圈
Owner 高章圈
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