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Selective nerve fiber stimulation for treating heart conditions

a heart condition and selective nerve technology, applied in the field of treating patients, can solve problems such as blocking of smaller-diameter fibers, and achieve the effects of reducing heart rate variability, improving variability, and modifying heart rate variability of subjects

Inactive Publication Date: 2008-05-29
MEDTRONIC INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This approach enables fine control over heart rate with improved stability and reduced muscle fatigue, allowing for more natural and effective treatment of heart conditions by selectively stimulating medium-diameter fibers and inhibiting larger ones.

Problems solved by technology

When such techniques are not used, the virtual cathode effect generally hinders blocking of smaller-diameter fibers, because a relatively large anodal current is typically necessary to block such fibers, and this same large anodal current induces the virtual cathode effect.

Method used

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  • Selective nerve fiber stimulation for treating heart conditions
  • Selective nerve fiber stimulation for treating heart conditions
  • Selective nerve fiber stimulation for treating heart conditions

Examples

Experimental program
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Embodiment Construction

[0399]FIG. 1 is a block diagram that schematically illustrates a vagal stimulation system 18 comprising a multipolar electrode device 40, in accordance with an embodiment of the present invention. Electrode device 40 is applied to a portion of a vagus nerve 36 (either a left vagus nerve 37 or a right vagus nerve 39), which innervates a heart 30 of a patient 31. Typically, system 18 is utilized for treating a heart condition such as heart failure and / or cardiac arrhythmia. Vagal stimulation system 18 further comprises an implanted or external control unit 20, which typically communicates with electrode device 40 over a set of leads 42. Control unit 20 drives electrode device 40 to (i) apply signals to induce the propagation of efferent nerve impulses towards heart 30, and (ii) suppress artificially-induced afferent nerve impulses towards a brain 34 of the patient, in order to minimize unintended side effects of the signal application. The efferent nerve pulses in vagus nerve 36 are i...

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Abstract

Apparatus is provided that includes an electrode device, adapted to be coupled to a vagus nerve of a subject, and a control unit, adapted to drive the electrode device to apply to the vagus nerve a current that reduces heart rate variability of the subject. Also provided is a method comprising applying to a vagus nerve of a subject a current that reduces heart rate variability of the subject.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]The present patent application is a continuation-in-part of PCT Patent Application PCT / IL03 / 00431, filed May 23, 2003, entitled, “Selective nerve fiber stimulation for treating heart conditions,” which:[0002](a) is a continuation-in-part of U.S. patent application Ser. No. 10 / 205,475, filed Jul. 24, 2002, entitled, “Selective nerve fiber stimulation for treating heart conditions,” which is a continuation-in-part of PCT Patent Application PCT / IL02 / 00068, filed Jan. 23, 2002, entitled, “Treatment of disorders by unidirectional nerve stimulation,” which is a continuation-in-part of U.S. patent application Ser. No. 09 / 944,913, filed Aug. 31, 2001, entitled, “Treatment of disorders by unidirectional nerve stimulation,” and[0003](b) claims the benefit of U.S. Provisional Patent Application 60 / 383,157 to Ayal et al., filed May 23, 2002, entitled, “Inverse recruitment for autonomic nerve systems.”[0004]Each of the above-referenced applications is...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61N1/365A61NA61N1/05A61N1/18A61N1/36A61N1/362
CPCA61B5/024A61B5/412A61N1/0551A61B5/7217A61N1/36114A61N1/3621A61N1/3627A61N1/0556A61B5/4029A61B5/4041
Inventor BEN-DAVID, TAMIRAYAL, SHAIBEN-EZRA, OMRYCOHEN, EHUD
Owner MEDTRONIC INC
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