Process for discriminating between biological states based on hidden patterns from biological data
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
a biological data and hidden pattern technology, applied in the field of biological data hidden pattern processing, can solve the problems of linearity of statistical methods, statistical models that are not robust with respect to non-linear data, and the limitations of statistical methods
Inactive Publication Date: 2005-02-24
ASPIRA WOMENS HEALTH INC +1
View PDF21 Cites 10 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
However, statistical methods have some limitations in that they are often linear, at least in their simple, well-known forms such as multivariate linear regressions.
Furthermore, statistical models tend not to be robust with respect to non-linear data.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0027] The invention comprises a) creating a data stream representing the biological data (or combinations of data streams representing the biological data with clinical, health, or non-biological data) and abstraction of that data into characteristic vectors; b) the discovery of hidden diagnostic patterns of molecular expression (i.e. pattern discovery); and c) determining which biological state of interest such a pattern of molecular expression represents. The molecules of interest may comprise, but are not limited to, proteins, peptides, RNA, DNA, etc. The biological samples comprise, but are not limited to serum, blood, saliva, plasma, nipple aspirants, synovial fluids, cerebrospinal fluids, sweat, urine, fecal matter, tears, bronchial lavage, swabbings, needle aspirantas, semen, vaginal fluids, pre-ejaculate, etc.
[0028] The biological states of interest may be a pathologic diagnosis, toxicity state, efficacy of a drug, prognosis of a disease, stage of a disease, biological sta...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Property
Measurement
Unit
molecular weight
aaaaa
aaaaa
time of flight
aaaaa
aaaaa
mass spectrum
aaaaa
aaaaa
Login to view more
Abstract
The invention describes a process for determining a biological state through the discovery and analysis of hidden or non-obvious, discriminatory biological data patterns. The biological data can be from health data, clinical data, or from a biological sample, (e.g., a biological sample from a human, e.g., serum, blood, saliva, plasma, nipple aspirants, synovial fluids, cerebrospinal fluids, sweat, urine, fecal matter, tears, bronchial lavage, swabbings, needle aspirantas, semen, vaginal fluids, pre-ejaculate.), etc. which is analyzed to determine the biological state of the donor. The biological state can be a pathologic diagnosis, toxicity state, efficacy of a drug, prognosis of a disease, etc. Specifically, the invention concerns processes that discover hidden discriminatory biological data patterns (e.g., patterns of protein expression in a serum sample that classify the biological state of an organ) that describe biological states.
Description
[0001] This application claims benefit under 35 U.S.C. sec. 119(e)(1) of the priority of application Serial No. 60 / 232,909, filed Sep. 12, 2000, Serial No. 60 / 278,550, filed Mar. 23, 2001, Serial No. 60 / 219,067, filed Jul. 18, 2000, and U.S. Provisional Application titled “A Data Method Algorithm Reveals Disease with Protein Signal of Ovarian and Prostate Cancer in Serum,” (Serial. No. to be assigned), filed May 8, 2001 which is hereby incorporated by reference in its entirety.I. FIELD OF THE INVENTION [0002] The field of the invention concerns a process for determining a biological state through the discovery and analysis of hidden or non-obvious, discriminatory biological data patterns. The biological data can be from health data, clinical data, or from a biological sample, (e.g., a biological sample from a human, e.g., serum, blood, saliva, plasma, nipple aspirants, synovial fluids, cerebrospinal fluids, sweat, urine, fecal matter, tears, bronchial lavage, swabbings, needle aspir...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more
Patent Type & Authority Applications(United States)