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Chinese medicine composition for treating osteoporosis and preparing method

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation method and quality control, can solve the problems of high incidence, high cost, heavy burden, etc.

Active Publication Date: 2006-10-25
HANDAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

That is: the incidence rate is high (about 20% for men, 1 / 3 for postmenopausal women aged 60 to 70, and as high as 2 / 3 for women over 80 years old); the cause of the disease is still unclear (multiple causes and multiple effects); treatment methods are diverse; High mortality rate (multiple, multi-site fractures, resulting complications, the mortality rate is 15% to 20%); high cost (requires long-term treatment, which brings heavy burden to family and society)

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example

[0053] Experimental example: clinical research experiment

[0054] Adopt random double-blind, positive medicine (Gushukang granule) parallel control, wherein 319 examples of pharmaceutical composition of the present invention, 100 examples of Gushukang granule. The comprehensive curative effect result shows: 1. the total effective rate of the comprehensive curative effect of the pharmaceutical composition of the present invention is 84.95%, and the marked rate is 46.39%; the total effective rate of the control group is 72.00%, and the marked rate is 38.00% %, there was a significant difference between the test group and the control group. 2. The total effective rate of the comprehensive curative effect of the pharmaceutical composition of the present invention is 97.18% for syndrome differentiation of liver and kidney deficiency, and the control efficiency is 56.43%; %, the control efficiency was 41.00%, and the difference between the test group and the control group was sign...

Embodiment 1

[0068] Embodiment 1: the preparation of granule

[0069] Rehmannia glutinosa 40kg, dogwood 35kg, epimedium 30kg, yam 25kg

[0070] Alisma 40kg, Moutan Bark 20kg, Wolfberry 40kg, Cistanche 35kg

[0071] Cuscuta 25kg Poria cocos 30kg Oyster 60kg

[0072] Take Cornus officinalis and Moutan cortex, add ethanol to reflux and extract twice, combine the extracts, and filter; add water to decoct the residue and other rehmannia glutinosa and other nine flavors for three times, filter, concentrate the filtrate, alcohol precipitation, filter, and the filtrate is the same as the above The ethanol extracts are combined, the ethanol is recovered, and concentrated into a thick paste, which is added with auxiliary materials, stirred evenly, granulated, and dried to obtain the product.

Embodiment 2

[0073] Embodiment 2: the preparation of capsule

[0074] Rehmannia glutinosa 25kg, dogwood 45kg, epimedium 15kg, yam 40kg

[0075] Alisma 25kg, Moutan bark 35kg, Lycium barbarum 30kg, Cistanche 55kg

[0076] Cuscuta 15kg Poria cocos 45kg Oyster 35kg

[0077] Take Cornus officinalis and Moutan cortex, add ethanol to reflux and extract 3 times, combine the extracts, and filter; add water to decoct the residue and other nine flavors such as Rehmannia glutinosa twice, filter, concentrate the filtrate, alcohol precipitation, filter, and the filtrate is the same as the above The alcohol extracts are combined, the ethanol is recovered, and concentrated into a thick paste, and conventional auxiliary materials are added to make capsules according to the conventional process.

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Abstract

The present invention relates to a Chinese medicine composition for effectively curing osteoporosis and its related diseases and its preparation process. It is made up by using 11 Chinese medicinal materials of cooked rehmannia root, cornus fruit, Chinese yam, epimedium, alisma tuber and others through a certain preparation process. It can be made into tablet, oral liquor, granules and injection, etc.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, a preparation method and a quality control method thereof, in particular to a traditional Chinese medicine composition for treating osteoporosis, a preparation method and a quality control method thereof. Background technique [0002] With the aging of the population, the incidence of osteoporosis is increasing, which has attracted the attention of governments of various countries. The World Health Organization designated October 20th as "World Osteoporosis Day". For example, in 1998, the theme was "Government Action", illustrating the social nature of the disease. In 2000, the theme was "Invest in Your Bones". , this subject has continued until now, explaining the status and role of prevention and treatment of osteoporosis in health care. [0003] Osteoporosis is a systemic metabolic bone disease, manifested as decreased bone mineral content, changes in bone fine structure, decrease...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K35/618A61P19/10
Inventor 李恩陈致慜李春雷
Owner HANDAN PHARMA
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