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Periploca sepium fat soluble component extract no public pollution fishing medicine and its preparing method

A technology of extract and willow fat, which is applied in the field of fish parasitic monogenetic trematode control agent, to achieve the effect of not easy to produce drug resistance, not affecting feeding and growth, and low cost

Inactive Publication Date: 2006-03-22
NORTHWEST UNIV(CN)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

From the point of view of the use effect, there is no drug that can completely kill parasites at present. Several drugs are often used in combination in various regions to solve the problem of drug resistance, which has a certain effect on improving the killing of monogenetic trematodes.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Weigh 50 kg of dried and crushed willow root bark and stem bark, extract with methanol at 60°C under reflux, concentrate the extract and evaporate the methanol to liquid extract, extract with anhydrous industrial alcohol, and concentrate the extract to 5 kg;

[0026] The transdermal agent Azone and the emulsifier 1702-4 are uniformly mixed according to the weight ratio of 3:1 and prepared as a surfactant for later use.

[0027] Add 1 kg of the above-mentioned surfactant, 5 kg of bark root bark and stem skin fat-soluble component extract, and 19 kg of ethanol into a homogenizer for mixing, and mix uniformly at 50° C. to obtain the fish medicine of bark willow extract.

Embodiment 2

[0029] Weigh 50 kg of dried and crushed bark root bark and stem bark, extract with methanol at 65°C under reflux, concentrate the extract and evaporate the methanol to liquid extract, extract with anhydrous industrial alcohol, and concentrate the extract to 7 kg;

[0030] Dimethyl sulfoxide and emulsifier OP-10 are uniformly mixed according to the weight ratio of 3:2 to prepare as surfactant for later use.

[0031] Add 1 kg of the above-mentioned surfactant, 7 kg of the root bark of the willow bark, the fat-soluble component extract of the stem bark, and 5 kg of ethanol into a homogenizer for mixing, and mix evenly at 55° C. to obtain the fish medicine of the willow bark extract.

Embodiment 3

[0033] Weigh 50 kg of dried and crushed bark root bark and stem bark, extract with methanol reflux at 70°C, concentrate the extract and evaporate the methanol to liquid extract, extract with anhydrous industrial alcohol, and concentrate the extract to 6 kg;

[0034] The transdermal agent Azone and the emulsifier EL-10 are uniformly mixed according to the weight ratio of 5:1 to prepare as a surfactant for future use.

[0035] Add 1 kg of the above-mentioned surfactant, 6 kg of bark willow root bark, stem bark fat-soluble component extract, and 3 kg of ethanol into a homogenizer and mix them uniformly at 60° C. to obtain the fish medicine of willow bark extract.

[0036] Above-mentioned embodiment can enumerate a lot, does not enumerate one by one again here, proves from the data obtained from the large amount of experiments that the applicant has done, as long as select within the parameter scope of technical scheme of the present invention, can prepare and reach the object of t...

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PUM

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Abstract

The present invention discloses fish medicine with the liposoluble extract of Periploca sepium as main component. The technological key points include extracting liposoluble extract with Periploca sepium root and stem bark and through crushing, methanol reflux extraction at 60-70 deg c, and concentrating the extracted liquid to 10-15 wt% of material; and compounding the fish medicine with liposoluble extract of Periploca sepium as active component in 20-75 wt%, surfactant in 3-10 wt% and solvent as the rest part. Compared with chemical fish medicine, the fish medicine with the liposoluble extract of Periploca sepium as main component has the advantages of no influence on aquatic product quality, no residue, no pollution, less drug resistance, safety on aquatic product, etc.

Description

technical field [0001] The invention belongs to an insecticide and a control agent in the aquaculture industry, in particular to a fish parasitic monogenetic trematode control agent mainly composed of Periploca sepium extract. Background technique [0002] Fish ectoparasitic monogenetic flukes are one of the most serious diseases that harm aquaculture, especially the ringworms and ringworms that parasitize the gills of fish. A large number of parasitism leads to a large number of devastating fish deaths, often causing aquaculture industry Huge economic loss. Regarding the prevention and treatment of such parasitic diseases, for a long time, only a few types of drugs have been repeatedly used, which has increased the dosage of drugs year by year, and the drug resistance of parasites has also increased. At present, there is no good alternative medicine at home and abroad. The current prevention and control of ringworm and ringworm disease at home and abroad are still some co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/76A61P33/14A61P33/00A01N65/00
Inventor 申烨华张芳玲王高学刘建玲郝康林
Owner NORTHWEST UNIV(CN)
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