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Atomizing agent containing medicinal plant oil

A spray and vegetable oil technology, applied in the field of medicine, can solve the problems of spray stability reduction, high volatility, drug stability reduction, etc.

Inactive Publication Date: 2006-03-08
晏四平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, such high concentrations of ethanol are unacceptable for many patients
Moreover, due to the high volatility of ethanol, the stability of the spray is reduced, that is, ethanol slowly volatilizes during long-term storage, and can carry some volatile medicinal vegetable oils to volatilize, thereby reducing the stability of the drug.
[0009] Judging from the existing technology, there is no spray product of medicinal vegetable oil that can fully meet the above four basic requirements for sprays.

Method used

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  • Atomizing agent containing medicinal plant oil
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  • Atomizing agent containing medicinal plant oil

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] Example 1 ——Use castor oil as medicinal vegetable oil to prepare sprays containing high-concentration drugs, mainly to investigate the main pharmacologically active ingredients in the sprays containing medicinal vegetable oils of the present invention, that is, the maximum dosage range of medicinal vegetable oils.

[0082] prescription:

[0083] Castor oil 50g

[0084] MIGLYOL  810 add to 100ml

[0085] Preparation: Take castor oil and add 50ml of MIGLYOL  810, stir to dissolve, then add MIGLYOL  810 to 100ml, stir evenly, filter with a dry G6 vertical melting glass filter, dispense into spray bottles, and screw the spray pump to get it.

[0086] In addition, a control sample was prepared according to the following prescription:

[0087] Control sample prescription:

[0088] Castor oil 50g

[0089] 98% ethanol to 100ml

[0090] Preparation method: Refer to the preparation method of the sample in Example 1 above.

[0091] Spray uniform...

Embodiment 2

[0093] Example 2 ——Preparing a spray with Suhexiang as medicinal vegetable oil, which contains a higher concentration of ethanol, and mainly investigates the taste of the medicinal liquid when the spray of the present invention contains a higher concentration of ethanol.

[0094] prescription:

[0095] Su Hexiang 10g

[0096] 98% ethanol 40g

[0097] Milk chocolate flavor 10g

[0098] MIGLYOL  810 add to 100ml

[0099] Preparation: Take Su He Xiang, add ethanol to dissolve, add flavor and 30ml MIGLYOL  , Stir to dissolve, then add MIGLYOL  To 100ml, stir evenly, filter with a dry G6 vertical melting glass filter, dispense into spray bottles, tighten the spray pump, and get it. In addition, a control sample was prepared according to the following prescription:

[0100] Control sample prescription:

[0101] Su Hexiang 10g

[0102] Milk chocolate flavor 10g

[0103] 98% ethanol to 100ml

[0104] Preparation: Take Suhexiang and milk chocolate e...

Embodiment

[0106] Example samples: iv) Easy to accept.

[0107] Control sample: ii) Reluctantly accepted.

[0108] It can be seen that when the present invention contains a higher concentration of ethanol (40g / 100ml), the mouthfeel of the spray prepared is still better than the mouthfeel of the formulation without the oily liquid carrier of the present invention. It is easy to infer that when the amount of ethanol is low, or when there is no ethanol at all, the sprays made can get a good mouth feel. When the main ingredient of the medicinal vegetable oil causes a bad taste, you can add an appropriate amount of flavoring agent to improve it.

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PUM

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Abstract

The present invention provides a spray containing medicinal vegetable oil. The liquid medicine of said spray contains one or more than one medicinal vegetable oil with therapeutic action and effective dose and oleaginous liquid medicine carrier. The described oleaginous liquid medicine carrier is formed from one or more than one synthetic or natural fatty oil.

Description

【Technical Field】 [0001] The invention belongs to the technical field of medicine, and relates to a spray, in particular to a spray containing medicinal vegetable oil. 【Background technique】 [0002] Aromatic plants and essential oils have long been used extensively in traditional medicines such as Hippocrates and Ayurbeda. The legendary spice of the Greek era, "Merceae scented" is said to be able to cure "any inflammation." Ancient Greek physicians used various aromatic substances as medicines, and fumigation with aromatic substances was a means of curing diseases. In the 17th and 18th centuries, the distillation technology of essential oils made great progress, and it was an era when essential oils were used in large quantities in medicines and cosmetics. Starting in the middle of the 19th century, plant essential oils, like medicinal plants, were not used as therapeutic drugs by people. However, scientific progress has in turn proved the medical effects of plant essential oils...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00A61K9/12
Inventor 周华英
Owner 晏四平
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