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Composition of paeoniflorin and peony lactone glycoside with function of increasing leukocyte

A technology of paeoniflorin and increasing white blood cells, which is applied in the field of medicine

Inactive Publication Date: 2005-12-14
SHENYANG PHARMA UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no uniform standard for the extract of Paeoniae Alba. The total glucosides of paeony capsules on the market are preparations made from the effective parts extracted from the traditional Chinese medicine Paeoniae Alba. It has pharmacological effects such as anti-inflammatory and immune regulation. Rheumatoid Arthritis Treatment

Method used

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  • Composition of paeoniflorin and peony lactone glycoside with function of increasing leukocyte
  • Composition of paeoniflorin and peony lactone glycoside with function of increasing leukocyte
  • Composition of paeoniflorin and peony lactone glycoside with function of increasing leukocyte

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Experimental program
Comparison scheme
Effect test

Embodiment

[0054] 1. Dried Paeoniae Alba Radix slices 10Kg, boiled with water to extract twice, each time for 2 hours, the extract was filtered and passed through a reverse adsorption resin column, and then eluted with alcohol water, the eluent was concentrated and then chromatographed on a silica gel column to obtain The extract rich in paeoniflorin and paeonifloride components was finally decolorized by activated carbon, filtered, and the filtrate was concentrated under reduced pressure and dried in vacuum to obtain 150 g of the composition described in this patent (hereinafter referred to as the composition).

[0055] 2. 50g of this composition is mixed with 45g of microcrystalline cellulose and 5g of magnesium stearate, and the mixture is used for tableting. Each tablet weighs 0.2g, and each tablet contains 0.1g of this composition. According to the symptoms, take 1-2 tablets each time, 2-3 times a day.

[0056] 3. Combine 50g of this composition with 50g of cornstarch, add water to ...

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Abstract

The present invention relates to medicine composition extracted from Paeonia lactifora Pall and containing the active components paeoniflorin and albiflorin in the total content of 50-95 % and weight ratio of 0.1-10. The composition is suitable for being prepared into various medicine preparations, including delayed releasing preparation, controlled releasing preparation, body cavity administrated preparation, spray, transdermal preparation, oral preparation, injection and transfused fluid preparation alone or together with other medicine components. The composition is suitable for preparing medicine for treating leucopenia, throbocytopenia and achreocythemia of different causes.

Description

Technical field: [0001] The invention relates to the technical field of medicine, specifically, it is a composition of paeoniflorin and paeoniflorin which has the effect of raising white blood cells. Background technique: [0002] Paeoniae Alba is the dried root of the perennial herbaceous plant Paeoniae officinalis of the Paeoniaceae Paeoniaceae family. The so-called Radix Paeoniae Alba and Radix Paeoniae Rubra, according to the current application situation and the records in the herbal medicine of past dynasties, it can be considered that Radix Paeoniae Alba is the root of cultivated Radix Paeoniae Alba, and Radix Radix Radix Radix Rubrae mainly comes from the roots of wild Radix Paeoniae. Peony is distributed in the northern part of my country, and another grass peony P.obovata.Maxim. of the same genus is distributed in Northeast, North, Central, Southwest and other regions. Sichuan red peony P.veitchiiLynch. distribution in Gansu, Shanxi, Sichuan, Tibet and other provi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048
Inventor 游松郭丽清孙燕王慧敏曹颖林曹雅明
Owner SHENYANG PHARMA UNIVERSITY
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