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Anti-adhesion isolator

A spacer, anti-adhesion technology, applied in the fields of drug combination, surgical drugs, medical science, etc., can solve problems such as efficacy limitation

Inactive Publication Date: 2003-07-16
AMITIE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] Unfortunately, despite their achievements in anti-adhesion and hemostasis, the typical anti-adhesion barriers described above are still limited in efficacy, such as adhesive, substantive, anti-inflammatory, antibacterial, and regenerative properties

Method used

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specific Embodiment approach

[0042] The actual and currently preferred embodiments of the invention are illustrated in the following examples.

[0043] However, those skilled in the art should understand that in consideration of these contents, modifications and improvements can be made within the spirit and scope of the present invention.

[0044] In the following application examples, an anti-adhesion spacer with a specific shape is used, but in fact it can be modified into various shapes as needed, especially for those skilled in the art. Preparation of anti-adhesion spacer

preparation Embodiment 1

5.0

[0046] Finally, the shape produced is the powder described in (1) below or the foam described in (2).

[0047] (1) Dissolve each component in 90 mL of water, quickly freeze the solution by immersing it in liquid nitrogen, and then freeze-dry it at less than -55°C for more than 48 hours. Subsequently, a solid substance is generated, which is ground to prepare a powder for anti-blocking separator.

[0048] (2) Dissolve each component in 90 mL of water, and then pour it into a mold of a suitable shape, then immerse the solution in liquid nitrogen for rapid freezing, and then freeze-dry it at less than -55°C for more than 48 hours. Subsequently, a foam for anti-blocking spacers is formed. Naturally, it can also be ground into a powder similar to (1) of the anti-blocking separator.

[0049] According to the actual situation, in the methods mentioned in (1) and (2) above, the sterilization step can be performed at 120°C for 10 minutes before freeze-drying the solution. In v...

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Abstract

The present invention relates to anti-adhesion barriers which prevents an adhesion between tissues at an operated legion and have various shapes, comprising sodium carboxymethyl cellulose (NaCMC) and gellan gum in 1:(0.1~10) of weight ratio. The anti-adhesion barriers of the present invention prevent adhesions at the operated legion or between bleeding legion and existed tissues more effectively after self-transplantation and being sealed completely, than conventional anti-adhesion barriers do and moreover, have remarkable haemostatic effects, anti-inflammation adhesion and application effect.

Description

Technical field [0001] The present invention relates to an anti-adhesion spacer that inhibits bleeding in an operation area (hemostatic effect) and can significantly prevent adhesion between tissues in the operation area (anti-adhesion effect). Background technique [0002] Generally speaking, if there is a slight bleeding during or after the operation, there will be a lot of problems when the operation is performed again. The surgical area and bleeding area will adhere to the cells in the tissue, even after the suture is completed. [0003] In fact, it has been reported that adhesions can be caused after abdominal surgery, with a frequency of 70-95% (Eur. J. Surg., 1997, Suppl., 577, 10-16, 24-31, 32-39). In particular, the adhesion between organs during abdominal surgery, such as adhesion between the abdominal cavity wall and the intestine, is even more unfavorable. [0004] In order to solve these problems, people have conducted a lot of research to actively try to develop ant...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/00A61K31/198A61K31/4422A61K31/573A61K31/685A61K31/716A61K31/717A61K31/721A61K31/727A61K31/765A61K33/00A61K38/46A61L31/04A61P41/00
CPCA61L31/041A61P41/00C08L5/00C08L1/28
Inventor 金大植金度勋李廷权
Owner AMITIE
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