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Application of micromolecular cubilose peptide for preventing and improving skin inflammation

A skin inflammation and small molecule technology, applied in skin care preparations, skin diseases, anti-inflammatory agents, etc., can solve the problems of no relevant reports on the preparation process, large equipment cost, limited application scope, etc., and achieve good prevention and control. Therapeutic effect, good absorption properties, anti-inflammatory effect

Pending Publication Date: 2022-08-05
厦门市燕之屋丝浓食品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, the research on bird’s nest peptides mainly focuses on the following two categories. The first category mainly focuses on improving the utilization of bird’s nest protein. Although this type of research has improved the utilization of bird’s nest protein to a certain extent, there are generally complex preparation processes, The high cost of equipment and the lack of research on the efficacy of the obtained bird's nest peptide make the efficacy of the prepared bird's nest peptide unclear and the scope of application is limited, which is not conducive to promotion
The second category mainly focuses on the research of whitening function, immune function and anti-tumor effect. This kind of research is often not thorough enough to study the molecular weight of bird’s nest peptide. Generally, there is a problem that the molecular weight of bird’s nest peptide is relatively large, which is not conducive to the good absorption and utilization of the human body.
At present, there is no relevant report on the bird's nest peptide and its preparation process for anti-skin inflammation

Method used

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  • Application of micromolecular cubilose peptide for preventing and improving skin inflammation
  • Application of micromolecular cubilose peptide for preventing and improving skin inflammation
  • Application of micromolecular cubilose peptide for preventing and improving skin inflammation

Examples

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preparation example Construction

[0041] The embodiment of the present invention provides a preparation method of small molecule bird's nest peptide powder, comprising the following steps:

[0042] Soaking: Weigh a certain amount of dry bird's nest, add water to soak the bird's nest for 6 to 12 hours, and obtain the soaked bird's nest;

[0043] Heating: Supplement the foamed bird's nest with a certain amount of purified water, so that the ratio of material to liquid reaches 1-4:100 (ratio of dry bird's nest to purified water), and then heat to 80 ℃ ~ 120 ℃, and the heating time is 0.5h ~ 2h;

[0044] Enzymatic hydrolysis: Pour the above bird's nest solution into the enzymatic hydrolysis tank, adjust the pH to pH=3~9, heat up to 35℃~60℃, and add trypsin, pepsin, flavor protease, papain, neutral protease or alkali One or more enzyme preparations in the protease; and the added amount of the protease is 500~10000U / g, the enzymolysis time is 60min~360min, after the enzymolysis is completed, the temperature is raise...

Embodiment 1

[0051] Weigh the dry bird's nest of 1kg, soak the bird's nest with 6kg water for 6h, obtain the bird's nest after foaming; Supplement certain purified water in the above-mentioned materials, so that the material-liquid ratio reaches the dry bird's nest: purified water=1:100, and the heating temperature is 80 ℃, heating time is 2h; Pour the above bird's nest solution into the enzymatic hydrolysis tank, adjust the pH to pH=6, heat up to 50 ℃, and add neutral protease 2000U / g, the enzymatic hydrolysis time is 180min, after the enzymatic hydrolysis is over The temperature was raised to 100 °C, and the temperature was kept for 10 min; the above-mentioned enzymatic hydrolyzed solution was centrifuged, the centrifugal speed was 8000 rpm / min, and the time was 15 min to obtain the required small-molecule bird's nest peptide solution; the above-mentioned bird's nest solution was concentrated 5 times by single-effect evaporation; finally , the above-mentioned concentrated solution is drie...

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Abstract

The invention provides an application of a micromolecular cubilose peptide for preventing and improving skin inflammation, and the micromolecular cubilose peptide is used for eliminating the skin inflammation. The micromolecular cubilose peptide is easy to digest, absorb and utilize, has the effect of resisting skin inflammation, and is suitable for market popularization and application. The problems that the existing cubilose peptide is unclear in efficacy, limited in application range and not beneficial to popularization are solved, and the problems that the existing cubilose peptide preparation process is complex, the equipment cost investment is large, and the cubilose peptide molecular weight is large and not beneficial to human body absorption are solved. The micromolecular cubilose peptide can also be used for medicines, cosmetics, health care products, food, skin-friendly daily necessities and the like.

Description

technical field [0001] The invention relates to the application of a small molecule bird's nest peptide for preventing and improving skin inflammation. Background technique [0002] At present, the research on bird's nest peptides is mainly based on the following two categories. The first category mainly focuses on improving the utilization rate of bird's nest proteins. The cost of equipment is large, and the research on the efficacy of the obtained bird's nest peptide is lacking, which makes the efficacy of the prepared bird's nest peptide unclear, and the scope of application is limited, which is not conducive to promotion. The second category mainly focuses on the research on whitening function, immune function and anti-tumor effect. This kind of research is often not thorough enough on the molecular weight of bird's nest peptide, and there is generally a problem that the molecular weight of bird's nest peptide is relatively large, which is not conducive to good absorptio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01A61K8/64C12P21/06A61P17/00A61P29/00A61Q19/00
CPCC12P21/06A61K38/012A61K8/64A61Q19/00A61P17/00A61P29/00Y02A50/30
Inventor 范群艳银小倩詹华强董婷霞连建梅柳训才李鸿铭李有泉
Owner 厦门市燕之屋丝浓食品有限公司
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