Magnetic particle-based field-free line scan imaging and field-free point localization hyperthermia fusion device

Abstract

The invention belongs to the technical field of magnetic nanoparticle imaging and hyperthermia fusion, and in particular relates to a magnetic particle-based field-free line scanning imaging and field-free point positioning hyperthermia fusion device and method, aiming at solving the lack of images in existing magnetic fluid treatment methods Problems with guided therapy, precise thermal dose setting, non-invasive real-time temperature monitoring and precise localization. The device of the present invention includes: a magnet group, an induction coil, a living body bed, a control device, a display device, an image processing device, and a cooling system; the magnet group includes two sets of long curved magnet pairs and a cylindrical magnet; The two ends of the bending magnet are semi-circular rings, and the semi-circular rings are connected by two arcs constructed with a set curvature; the control device is configured to scan and image the target living object and perform hyperthermia on the set part. The invention realizes the magnetic fluid therapy with the characteristics of image-guided therapy, precise thermal dose setting, non-invasive real-time temperature monitoring and precise positioning.

Description

technical field [0001] The invention belongs to the technical field of magnetic nanoparticle imaging and hyperthermia fusion, and in particular relates to a field-free line scanning imaging and field-free point positioning hyperthermia fusion device and method based on magnetic particles. Background technique [0002] Magnetic fluid hyperthermia utilizes a suspension of magnetic nanoparticles, administered systemically or locally, combined with an externally applied alternating magnetic field, to ablate target tissue by generating heat through a process called induction. Heat generated at 37°C above mammalian body temperature induces apoptosis and / or enhances the sensitivity of target tissues to other therapies, such as radiotherapy and chemotherapy. While most hyperthermia techniques currently in development are aimed at cancer treatment, hyperthermia is also used to treat restenosis, remove plaque, ablate nerves, and reduce pain by increasing local blood flow. While magne...

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Problems solved by technology

[0005] In order to solve the above-mentioned problems in the prior art, that is, in order to solve the problems of image-guided treatment, precise thermal dose setting, non-invasive real-time temperature monitoring and precise positioning in the existing magnetic fluid therapy methods, the present invention proposes a magnetic fluid therapy based on Field-free line scanning imaging of particles and field-free point positioning hyperthermia fusion device, the device includes: a magnet group, an induction coil, a living bed, a control device, a display device, an image processing device, and a cooling system;

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