Traditional Chinese medicine composition for treating infertility and application thereof

A composition and infertility technology, applied in the directions of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., to achieve the effects of strict compatibility, improvement of reproductive function, and increased success rate of transplantation

Active Publication Date: 2022-05-13
SHANGHAI FIRST MATERNITY & INFANT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is no report about the traditional Chinese medicine composition of invigorating the kidney and nourishing essence, nourishing blood and benefiting the infertility caused by premature ovarian failure

Method used

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  • Traditional Chinese medicine composition for treating infertility and application thereof
  • Traditional Chinese medicine composition for treating infertility and application thereof
  • Traditional Chinese medicine composition for treating infertility and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1 treats the Chinese medicinal composition (1) of the infertility caused by premature ovarian failure

[0022] Take each raw material medicine by weight ratio: 30 parts of Ziheche, 30 parts of amethyst, 15 parts of Rehmannia glutinosa, 15 parts of Radix Paeoniae Alba, 9 parts of Atractylodes macrocephala, 15 parts of Cuscuta, 15 parts of Morinda officinalis, 15 parts of Cistanche, 15 parts of epimedium, 9 parts of curculigo, and 6 parts of licorice, add 10 times the amount and 8 times the amount of water to decoct each raw material twice, each time for 2 hours, filter respectively, combine the filtrates, and concentrate to the relative The density is 1.20 (80-85 degrees), let it cool, add 3 times the amount of ethanol, stir well, let stand, take the supernatant and filter, the filtrate is steamed without alcohol smell, let stand, take the supernatant and concentrate under reduced pressure to obtain The extract is dried and pulverized to make granules.

Embodiment 2

[0023] Embodiment 2 treats the Chinese medicine composition (two) of the infertility that premature ovarian failure causes

[0024] Take each raw material medicine by weight ratio: 30 parts of Ziheche, 30 parts of amethyst, 10 parts of Rehmannia glutinosa, 10 parts of Radix Paeoniae Alba, 12 parts of Atractylodes macrocephala, 16 parts of Cuscuta, 14 parts of Morinda officinalis, 14 parts of Cistanche, 16 parts of epimedium, 10 parts of curculigo, and 7 parts of licorice, add 10 times the amount and 8 times the amount of water to decoct each raw material twice, each time for 2 hours, filter separately, combine the filtrates, and concentrate to the relative The density is 1.20 (80-85 degrees), let it cool, add 3 times the amount of ethanol, stir well, let stand, take the supernatant and filter, the filtrate is steamed without alcohol smell, let stand, take the supernatant and concentrate under reduced pressure to obtain The extract is dried and pulverized to make granules.

Embodiment 3

[0025] Embodiment 3 treats the Chinese medicine composition (three) of the infertility that premature ovarian failure causes

[0026] Take each raw material medicine by weight ratio: 30 parts of Ziheche, 30 parts of amethyst, 20 parts of Rehmannia glutinosa, 20 parts of Radix Paeoniae Alba, 7 parts of Atractylodes macrocephala, 14 parts of Cuscuta, 16 parts of Morinda officinalis, 16 parts of Cistanche, 14 parts of Epimedium, 8 parts of curculigo, and 5 parts of Zhigancao, add 10 times the amount and 8 times the amount of water to decoct each raw material drug twice, each time for 2 hours, filter separately, combine the filtrates, and concentrate to the relative The density is 1.20 (80-85 degrees), let it cool, add 3 times the amount of ethanol, stir well, let stand, take the supernatant and filter, the filtrate is steamed without alcohol smell, let stand, take the supernatant and concentrate under reduced pressure to obtain The extract is dried and pulverized to make granules...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating infertility caused by premature ovarian failure. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 25-35 parts of human placenta, 25-35 parts of amethyst, 10-20 parts of prepared rehmannia root, 10-20 parts of radix paeoniae alba, 7-12 parts of bighead atractylodes rhizome, 14-16 parts of semen cuscutae, 14-16 parts of morinda officinalis, 14-16 parts of cistanche, 14-16 parts of herba epimedii, 8-10 parts of rhizoma curculiginis and 5-7 parts of honey-fried licorice root. The invention further provides application of the traditional Chinese medicine composition. According to the traditional Chinese medicine composition, the reproductive function of infertility patients caused by premature ovarian failure is improved, the total pregnancy rate of a traditional Chinese medicine group is increased compared with that of a DHEA group, and the transplantation success rate is obviously increased. The traditional Chinese medicine composition has the advantages that the traditional Chinese medicine composition is mild in medicine flavor, warm and tonify, both essence and blood are taken into consideration, kidney yang is warmly tonified without losing dryness, the kidney is nourished, the spleen is not cold, cool and greasy, the primary and secondary effects are clear, the compatibility is rigorous, simple and essential effects are achieved, and the effects of warmly tonify kidney yang, tonify spleen, supplement qi, regulate brewing and recuperating eggs are jointly achieved.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating infertility and its application. Background technique [0002] Human fertility gradually declines with age. The fundamental reason is the decline of ovarian function, that is, the simultaneous decline of the number of eggs and the quality of eggs. At the age of 30, women only retain 12% of their eggs, and at the age of 40, it drops to 3%. Age not only affects the number of eggs, but also has a serious impact on the quality of the eggs. The current treatment for premature ovarian failure is a combination of traditional Chinese and Western medicine. Western medicine includes youth hormone and artificial cycle to help restore ovarian function. After treatment, some people can return to normal ovulation, but it is not absolute, and it depends on the individual. After the comprehensive treatment of Chinese ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P15/08A61K35/50A61K33/14
CPCA61K35/50A61K33/14A61K36/804A61K36/71A61K36/65A61K36/284A61K36/39A61K36/43A61K36/746A61K36/64A61K36/296A61K36/88A61K36/484A61P15/08A61K2300/00
Inventor 马娟娟张勤华王铮翁晓晨吴胜男王照钦朱璐刘新宇裴建
Owner SHANGHAI FIRST MATERNITY & INFANT HOSPITAL
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