Method and device for identifying adverse drug reaction

Abstract

The invention relates to an adverse drug reaction identification method and device. The method comprises the following steps: acquiring medical record data of a patient using index drugs and label drugs in an investigation period from an electronic medical record system; using a pre-constructed general data model to extract standardized medical record data of the patient from the obtained medical record data to obtain a standardized data set; respectively confirming whether the first medicine and the second medicine in the index medicines can cause the adverse reaction treated by the label medicine or not; when all the index drugs cannot cause adverse reactions treated by the tag drugs, performing prescription sequence symmetric analysis on the index drugs and the tag drugs by using the obtained standardized data set, and outputting an analysis result; and according to an analysis result, determining whether the adverse reaction treated by the label medicine can be caused after the interaction of the index medicines. According to the method, the identification accuracy of the adverse reaction between the drugs is high, the speed is high, and therefore the level of the adverse reaction can be correctly evaluated.

Description

technical field [0001] The present application relates to the field of drug safety, in particular to a method and device for identifying adverse drug reactions. Background technique [0002] At present, the national drug administration department releases information on adverse drug reactions to the public, which is conducive to the general public's learning and mastering of drug knowledge and ensuring the lives, health and safety of the people. Therefore, monitoring adverse reactions of post-marketing drugs is very important for evaluating the safety and re-evaluation of real-world post-marketing drugs. At present, in the reporting of adverse drug reactions, passive spontaneous reports are mainly used as risk signals, but this kind of spontaneous reporting also has certain problems. On the one hand, the "denominator" number of exposed groups cannot be clearly determined, and the incidence of certain adverse reactions cannot be accurately calculated. ;The number of individu...

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Problems solved by technology

At present, in the reporting of adverse drug reactions, passive spontaneous reports are mainly used as risk signals, but this kind of spontaneous reporting also has certain problems. On the one hand, the "denominator" number of exposed groups cannot be clearly determined, and the incidence of certain adverse reactions cannot be accurately calculated. ;The number of individual case reports is largely uncontrollable, sometimes the underreporting phenomenon is serious, and sometimes a large number of adverse reactions may be reported intensively due to the influence of the media, resulting in the inability to correctly evaluate the level of adverse reactions; and these The existence of the problem further reduces the accurate determination of the adverse reaction of the drug

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