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A screening system for patients with panic disorder

A panic and disorder technology, applied in the field of panic disorder screening, can solve the problems of lack of early diagnosis methods for panic disorder, and achieve the effect of improving recognition

Active Publication Date: 2022-04-01
PEKING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is still a lack of effective early diagnosis methods for panic disorder. The present invention mainly screens and intervenes panic disorder patients through the generalization of attention regulation of pre-startle reflex inhibition.

Method used

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  • A screening system for patients with panic disorder
  • A screening system for patients with panic disorder

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Experimental program
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Effect test

Embodiment Construction

[0033] The present invention is described in further detail below in conjunction with specific examples.

[0034] 1. Test preparation

[0035] In the preparation stage, the subjects sit in a quiet environment (an anechoic room or a shielded room is ideal), and electrodes are installed on the subjects (electrode 1. 10 mm below the pupil; electrode 2: the outer side of electrode 1 near the corner of the eye; ground electrode located on the mastoid). After the electrodes were installed, sounds were played to the subjects through earphones, and at the same time, the EMG activity within the time window of 500 ms from the startle stimulus or the prepulse stimulus was started to be recorded.

[0036] 2. Test process

[0037] The subjects first adapted to the background noise for 5 minutes. Afterwards a PPI test is performed. In general, the test was divided into two trials: prepulse stimulus + startle stimulus and startle stimulus only. For the trial of prepulse stimulation + st...

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Abstract

The invention discloses a screening system for patients with panic disorder, which comprises a signal playing unit, a signal collecting unit and a signal processing platform. Compared with the past startle reflex prepulse suppression detection system, the prepulse stimulation played by the signal playback unit of the present invention uses monosyllable or two-syllable speech signals for the first time, including fear emotion speech, common negative speech, and neutral word speech three signal, and then for the first time introduced the semantic processing of the prepulse stimulus signal; the index calculated by the signal processing platform of the present invention not only includes the amplitude of the startle reflex and its prepulse suppression, but also investigates the effect of fear emotion attention and spatial attention on the regulation of PPI. The generalization effect, and then give guidance for the screening of panic disorder. The invention can quickly, simply and objectively screen for panic disorder aiming at major social events.

Description

technical field [0001] The invention belongs to the technical field of biology and new medicine, and specifically relates to a screening method for panic disorder, which takes the generalization of the attention adjustment of pre-startle reflex suppression as the key technical paradigm, including the use of negative vocabulary audio as stimulating materials and the orbicularis Myoelectricity as a key signal related technology. Background technique [0002] A sudden strong sensory stimulus will trigger the whole-body reflex activity of people or animals, which is called startle reflex. cognitive activities that interfere with normal cognitive processing. However, if a weak stimulus that is not sufficient to cause the startle reflex (ie, prepulse stimulation) is presented before a strong stimulus, it will inhibit the subsequent startle reflex, which is called prepulse inhibition of the startle reflex (prepulse inhibition, PPI) . PPI is a widely used sensorimotor gating meas...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/389A61B5/395A61B5/397A61B5/16A61B5/00
CPCA61B5/165A61B5/7235
Inventor 李量丁宇曲天书
Owner PEKING UNIV
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