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Fluid mixing by means of fluid supply lines with line-specifically associated fluid pumps for liquid chromatography

A fluid supply and liquid chromatography technology, which is applied in liquid variable volume machinery, solid adsorbent liquid separation, pumps, etc., to achieve the effect of easy operation

Pending Publication Date: 2020-10-20
AGILENT TECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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  • Fluid mixing by means of fluid supply lines with line-specifically associated fluid pumps for liquid chromatography
  • Fluid mixing by means of fluid supply lines with line-specifically associated fluid pumps for liquid chromatography
  • Fluid mixing by means of fluid supply lines with line-specifically associated fluid pumps for liquid chromatography

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Embodiment Construction

[0046] Before describing exemplary embodiments executed with reference to the accompanying drawings, some basic considerations from which exemplary embodiments of the present invention are derived will be summarized.

[0047] According to an exemplary embodiment of the present invention, in the fluid supply device, each fluid pump is arranged in a respective supply line downstream of each fluid component source. By actively or inactively switching the individual fluid pumps themselves and / or line-specific switching valves operatively coupled thereto, precise fluid composition can be achieved at the merging point of the supply lines, independent of the filling involved in the source of the fluid components. The effect of gravity on level or position height is irrelevant. The provision of such a separate and line- or channel-specific fluid pump avoids the gas phase, since the liquid is supplied under pressure in the suction region upstream of the fluid delivery device, in partic...

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Abstract

The invention relates to a liquid chromatography fluid supply device (150) for providing a mixture of several different fluids as a mobile phase for a liquid chromatography sample separation device (10), wherein the fluid supply device (150) comprises a plurality of supply lines (104 to 107), each fluidically coupled to a respective one of a plurality of fluid component sources (100 to 103) for providing a respective one of the fluids, a plurality of fluid pumps (51 to 54), each of which is associated with a respective one of the supply lines (104 to 107), and a combining point (87), at whichthe fluids from the supply lines (104 to 107) are to be combined, wherein each of the plurality of fluid pumps (51 to 54) does or does not convey a respective fluid from a respective one of the fluidcomponent sources (100 to 103) to the combining point (87) as a function of a respective switching state of the fluid supply device (150).

Description

technical field [0001] The present invention relates to a liquid chromatography fluid supply device, a liquid chromatography sample separation device and a method for supplying a liquid chromatography sample separation device with a mixture of several different fluids as mobile phase. Background technique [0002] In HPLC, a liquid (mobile phase) is usually moved at a very precisely controlled flow rate (e.g. in the range of microliters to milliliters per minute) and at high pressure (typically 20 to 1000 bar and above, currently up to 2000 bar) through a so-called A stationary phase (for example, in a chromatographic column) to separate the individual fractions of the sample liquid introduced into the mobile phase from each other, and at this high pressure, the compressibility of the liquid can be easily perceived. After passing through the stationary phase, separated fractions of the fluid sample are detected in a detector. Such an HPLC system is known, for example, from ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): F04B13/02F04B23/04B01D15/16G01N35/10G01N30/32G01N30/34
CPCF04B13/02F04B23/04G01N30/34B01D15/16G01N35/1097G01N2030/027G01N2030/347
Inventor 克莱门斯·普拉切特卡
Owner AGILENT TECH INC
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