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Preparation method of three monomeric compounds from medicinal plant Radix Melon and their antioxidative effects in vitro

A technology of medicinal plants and ground shoot melon, which is applied in the field of in vitro antioxidant effect, can solve the problems of weak research on the material basis of medicinal effects and no report of in vitro antioxidative effect, and achieve the effect supported by reliable theoretical basis and reliable experimental data

Active Publication Date: 2022-04-19
MINZU UNIVERSITY OF CHINA
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Problems solved by technology

[0005] Deficiency 1. The research on ground shoot melon at the stage mostly focuses on the identification of medicinal materials, artificial cultivation and preparation technology, etc., while the research on the material basis of its medicinal effect is relatively weak
[0006] Deficiency 2: At this stage, there is no report on the in vitro antioxidant effect of the above three monomeric compounds of ground shoot melon

Method used

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  • Preparation method of three monomeric compounds from medicinal plant Radix Melon and their antioxidative effects in vitro
  • Preparation method of three monomeric compounds from medicinal plant Radix Melon and their antioxidative effects in vitro
  • Preparation method of three monomeric compounds from medicinal plant Radix Melon and their antioxidative effects in vitro

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Embodiment Construction

[0016] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Apparently, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0017] 1. Separation and identification method of monomeric compounds:

[0018] Take 6.0kg of ground shoot melon and crush it, then heat and reflux extraction with 75% ethanol for 3 times, then heat and reflux with distilled water for 3 times, each time add ethanol with a volume of 20L and heat for 2h, combine the extracts for 6 times and concentrate under reduced pressure to 1.2kg of dry powder; redissolve the dry powder in distilled water, and then filter under reduced pres...

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Abstract

The invention belongs to the technical field of ground shoot melon research, and specifically relates to a method for preparing three monomer compounds from the medicinal plant ground shoot melon and its in vitro antioxidative effect. The invention provides a method for preparing three kinds of monomeric compounds from the medicinal plant Melon Gourd, and for the first time, three monomeric compounds (Hypericum wort) which have not been reported in this plant are isolated and prepared from the medicinal plant Melon glycosides, dihydroquercetin and adenosine), and carried out the research on the antioxidant effect of three monomeric compounds in vitro, which will provide a basis for the future development of the treatment of related diseases (cardiovascular diseases) , arthritis, age-related macular degeneration, neurasthenia, etc.) provide reliable experimental data support and theoretical basis.

Description

technical field [0001] The invention relates to the technical field of ground shoot melon research, and more specifically relates to a method for preparing three monomer compounds from the medicinal plant ground shoot melon and its in vitro antioxidative effect. Background technique [0002] Ground shoot melon (Cynanchum Thesioides (Freyn.) K. Schum), Mongolian name Temo-huhu or Temugen-huhu[1], also known as ground shoot flower, female Jing, horse grandma, etc., belongs to the angiosperm phylum Asclepiadaceae (Asclepiadaceae) genus Cynanchum is a perennial xerophytic upright semi-shrub, belonging to authentic medicinal materials in Inner Mongolia. It is often recorded in "Chinese Materia Medica" and "Mongolian Medicine Canon" that ground shoot melon is a perennial xerophyte with relatively strong economic attributes. The whole plant and its fruit can also be used as medicine. It has the effects of nourishing lung qi, clearing heat and relieving fire, promoting body fluid a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07H17/07C07H1/08C07H19/167C07D311/32C07D311/40A61P39/06A61P9/00A61P19/02A61P27/02A61P25/00
CPCC07H17/07C07H1/08C07H19/167C07D311/32C07D311/40A61P39/06A61P9/00A61P19/02A61P27/02A61P25/00
Inventor 裴凌鹏燕梦云薛帆黄火强乌恩奇令亚琴
Owner MINZU UNIVERSITY OF CHINA
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