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Traditional Chinese medicine prescription information detection method and detection system for rheumatoid arthritis clinical treatment

A rheumatoid and clinical treatment technology, applied in the field of traditional Chinese medicine prescription information detection methods and detection systems for the clinical treatment of rheumatoid arthritis, can solve the problem of ineffective treatment of rheumatoid arthritis, the ineffective target and mechanism of Bibishu Clarify and other issues to achieve the effect of improving treatment effect and quality of life, saving manpower, and increasing acceptance

Pending Publication Date: 2020-08-18
武汉市第一医院
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the target and mechanism of the action of Pangbishu are still unclear.
[0003] To sum up, the problem existing in the prior art is that the target and mechanism of the action of Miaobishu are not yet clear
For rheumatoid arthritis, there is no specific medicine at present, and most western medicines can only control inflammation and pain to a certain extent, and cannot effectively treat rheumatoid arthritis

Method used

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  • Traditional Chinese medicine prescription information detection method and detection system for rheumatoid arthritis clinical treatment
  • Traditional Chinese medicine prescription information detection method and detection system for rheumatoid arthritis clinical treatment
  • Traditional Chinese medicine prescription information detection method and detection system for rheumatoid arthritis clinical treatment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0136] 1. 120 cases in the treatment group and 60 cases in the control group:

[0137] Table 1 Two groups of ACR index improvement situation comparison (example, %)

[0138]

[0139] Compared with the control, *P<0.05

[0140] Table 2 Comparison of curative effect parameters before and after treatment in the two groups (divided into )

[0141]

[0142] Compared with this group before treatment, *P<0.05: compared with this group after treatment, △P<0.0.5.

[0143] 2. 40 cases in the treatment group and 40 cases in the control group:

[0144] 1) The impact on the total score of TCM symptoms: There was no significant difference in the symptom scores between the two groups before treatment (P>0.05), which was not statistically significant. After treatment, the symptom scores of the two groups were significantly decreased, with a significant difference (P<0.01); after treatment, there was a significant difference between the symptom scores of the two groups (P<0.05). Se...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine prescription treatment, and discloses a traditional Chinese medicine prescription information detection method and detection system for rheumatoid arthritis clinical treatment. The traditional Chinese medicine prescription information detection method for rheumatoid arthritis clinical treatment comprises the following steps: receiving prescription information, and judging and comparing the prescription information; constructing a rheumatoid arthritis animal model; determining a treatment effect of Wangbishu (medicinefor relieving bone bending and rheumatism) on RA and a regulation and control effect mechanism on Th17 / Tregs; determining a regulation and control action mechanism of Wangbishu on Th17 / Tregs; and observing the change of clinical symptoms and signs of Wangbishu on the rheumatoid arthritis. The invention discloses an effect of an IL2 / STAT5 / Foxp3 or IL-23R / ROR gamma tx signal path in Th17 / Tregs balance, and provides a theoretical basis and an experimental basis for further popularization and development of treating RA with Wangbishu.

Description

technical field [0001] The invention belongs to the technical field of detection of traditional Chinese medicine prescriptions, in particular to a method and system for detecting information of traditional Chinese medicine prescriptions used for clinical treatment of rheumatoid arthritis. Background technique [0002] Currently, the closest prior art: Rheumatoid arthritis (RA) is a chronic systemic disease with unknown etiology, mainly inflammatory synovitis. It is characterized by polyarticular, symmetrical, and aggressive arthritis of the small joints of the hands and feet, often accompanied by involvement of extra-articular organs and positive serum rheumatoid factor, which can lead to joint deformities and loss of function. The pathogenesis of RA may be related to heredity, infection, and sex hormones. The pathology of RA arthritis mainly includes the proliferation of synovial lining cells, the infiltration of a large number of inflammatory cells in the interstitium, th...

Claims

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Application Information

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IPC IPC(8): G16H10/20G16H20/90G16H50/20
CPCG16H10/20G16H20/90G16H50/20
Inventor 万彬彬沈婷
Owner 武汉市第一医院
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