Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of degradable medical material and preparation method thereof

A raw material, silicone rubber technology, applied in the field of degradable medical materials and their preparation, can solve the problems of cracking and brittleness, and achieve the effect of expanding the application field, reducing the shrinkage rate, and improving the use value

Active Publication Date: 2022-04-26
HEFEI GENIUS NEW MATERIALS
View PDF8 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the high crystallinity of PHA materials, they are prone to brittleness and cracking in actual use, which limits the application of PHA materials in the pharmaceutical industry

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of degradable medical material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The poly-β-hydroxybutyric acid 85 parts, silicone rubber 10 parts, heat stabilizer 0.5 parts added to the vacuum mixer, mixed evenly for 1min, and then added surface modified chitin whiskers to it 5 parts, continue to mix for 1min, and finally add 0.2 parts of silicone rubber vulcanizer to it after 5 minutes of mixing can be opened, or by pulling strips through the mouth mold to obtain degradable medical materials. Among them, the processing temperature of the mixer is 200 °C, the pressure of the upper pressure is 0.65MPa, and the screw speed of the mixer is 30r / min.

Embodiment 2

[0030] The β-hydroxybutyric acid and β-hydroxyvaleric acid copolymer 77 parts, silicone rubber 15 parts, heat stabilizer 0.5 parts added to the vacuum mixer, mixed evenly for 2 min, and then added surface modified chitin whisker 8 parts, continue to mix for 2 min, and finally add 0.3 parts of silicone rubber vulcanizer to it after 7 minutes of mixing, or by granulation of the mold strip to obtain degradable medical materials. Among them, the processing temperature of the mixer is 195 °C, the pressure of the upper pressure is 0.65MPa, and the screw speed of the mixer is 40r / min.

Embodiment 3

[0032] 70 parts of polyhydroxybutyrate, 20 parts of silicone rubber, 0.5 parts of heat stabilizer are added to the vacuum mixer, mixed evenly for 3min, and then added to it 10 parts of surface modified chitin whiskers, continue to mix for 3min, and finally add 0.4 parts of silicone rubber vulcanizer to it after 10 minutes of mixing, or through the mouth mold strip granulation to obtain degradable medical materials. Among them, the processing temperature of the mixer is 190 °C, the pressure of the upper pressure is 0.65MPa, and the screw speed of the mixer is 50r / min.

[0033] The properties of the degradable medical material prepared in Examples 1-3 are shown in Table 1 below:

[0034] Table 1

[0035] Test projects / units Test standards Example 1 Example 2 Example 3 Density / g / cm 3

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
melting pointaaaaaaaaaa
Login to View More

Abstract

The invention discloses a degradable medical material and a preparation method thereof, which is prepared from the following raw materials in parts by mass: PHA materials, silicone rubber, surface-modified chitin whiskers, silicone rubber vulcanizing agent, heat-stabilizing The agent is prepared by step-by-step mixing. The present invention uses degradable PHA material as the base material, and uses dynamic vulcanization technology to uniformly mix silicone rubber with good biocompatibility into the base material as a toughening agent, and uses degradable surface-treated chitin whiskers as a toughening agent. Filled with reinforcing agent, a degradable composite material with excellent rigidity and toughness is obtained.

Description

Technical field [0001] The present invention relates to the field of general plastics, specifically to a degradable medical material and a method of preparation thereof. Background [0002] Biomedical materials are materials used to diagnose, treat, repair or replace diseased tissues, organs or enhance the function of an organism. It is the basis for the study of artificial organs and medical devices, and has become an important branch of contemporary materials disciplines, especially with the vigorous development of biotechnology and major breakthroughs, biomedical materials have become a hot spot for scientists from all over the world to compete for research and development. Biomedical materials are divided into inert biomedical materials, active biomedical materials, and bio-medical materials that can be degraded and absorbed according to the biochemical reaction level of the material in the physiological environment. Medical polymer materials are the earliest developed, most...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C08L67/04C08L83/07C08L5/08C08K5/14
CPCC08L67/04C08L2205/03C08L2205/16C08L2201/06C08L83/04C08L5/08C08K5/14
Inventor 杨桂生赵鑫朱敏
Owner HEFEI GENIUS NEW MATERIALS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com