Pharmaceutical composition for treating amblyopia

A composition and drug technology, applied in the directions of drug combination, drug delivery, drug formulation, etc., can solve problems such as lack of oral administration, and achieve significant effects

Active Publication Date: 2020-07-03
四川省中医药科学院中医研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Existing Chinese medicine compositions about the treatment of amblyopia have come out, but mostly external adjuvant therapy is main, as patent CN108404052A discloses a kind of pharmaceutical composition of prevention and treatment of myopia, amblyopia, it reaches the purpose of treating eye disease by external application exactly, still lacks at present Oral, effective Chinese medicine composition for the treatment of amblyopia, especially for children with amblyopia

Method used

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  • Pharmaceutical composition for treating amblyopia
  • Pharmaceutical composition for treating amblyopia
  • Pharmaceutical composition for treating amblyopia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1, the preparation of pharmaceutical composition of the present invention

[0034] Recipe: 167g Polygonum multiflorum, 167g Cistanche, 167g Rehmannia glutinosa, 167g medlar, 167g Cuscuta salt, 167g Alisma, 167g Salvia, 100g Chuanxiong, 100g tangerine peel.

[0035] Preparation method: Take the above-mentioned Jiuwei decoction pieces, add water to reflux, extract and decoct three times (add 10 times the amount of water each time), each time for 0.5 hours, filter through a 200-mesh filter, and concentrate under reduced pressure (temperature 65°C, vacuum degree -0.08~- 0.1Mpa) into an extract with a relative density of 1.35-1.40 (60°C), add dextrin equivalent to the extract, dry under normal pressure (60°C), powder the dried product, grind it, and use 80% Alcohol wet granulation, drying at 60°C, sieving, and collecting the granules of No. 1 to No. 5 sieves to obtain 1000 g of granules, and each gram of granules is equivalent to 1.37 g of raw medicinal materials....

Embodiment 2

[0036] Embodiment 2, the preparation of pharmaceutical composition of the present invention

[0037] Formula: Polygonum multiflorum 117g, Cistanche 117g, rehmannia glutinosa 117g, medlar 117g, dodder salt 117g, Alisma 117g, salvia miltiorrhiza 117g, chuanxiong 70g, tangerine peel 70g.

[0038] Preparation method: Take the above-mentioned Jiuwei decoction pieces, add water to reflux, extract and decoct three times (add 10 times the amount of water each time), each time for 0.5 hours, filter through a 200-mesh filter, and concentrate under reduced pressure (temperature 65°C, vacuum degree -0.08~- 0.1Mpa) into an extract with a relative density of 1.35-1.40 (60°C), add dextrin equivalent to the extract, dry under normal pressure (60°C), powder the dried product, grind it, and use 80% Alcohol wet granulation, drying at 60°C, sieving, and collecting the granules from No. 1 to No. 5 sieves.

Embodiment 3

[0039] Embodiment 3, the preparation of pharmaceutical composition of the present invention

[0040] Recipe: Polygonum multiflorum 217g, Cistanche 217g, rehmannia glutinosa 217g, medlar 217g, dodder salt 217g, Alisma 217g, salvia miltiorrhiza 217g, chuanxiong 130g, tangerine peel 130g.

[0041] Preparation method: Take the above-mentioned Jiuwei decoction pieces, add water to reflux, extract and decoct three times (add 10 times the amount of water each time), each time for 0.5 hours, filter through a 200-mesh filter, and concentrate under reduced pressure (temperature 65°C, vacuum degree -0.08~- 0.1Mpa) into an extract with a relative density of 1.35-1.40 (60°C), add dextrin equivalent to the extract, dry under normal pressure (60°C), powder the dried product, grind it, and use 80% Alcohol wet granulation, drying at 60°C, sieving, and collecting the granules from No. 1 to No. 5 sieves.

[0042] The beneficial effects of the present invention are illustrated below through test...

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Abstract

The invention discloses a pharmaceutical composition for treating amblyopia. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 117-217 parts of prepared fleeceflower root, 117-217 parts of herba cistanches, 117-217 parts of prepared rehmannia root, 117-217 parts of fructus lycii, 117-217 parts of semen cuscutae processed with salt-water, 117-217 partsof rhizoma alismatis, 117-217 parts of danshen root, 70-130 parts of rhizoma ligustici Chuanxiong, and 70-130 parts of dried tangerine peel. The pharmaceutical composition provided by the invention has the effect of treating the amblyopia, especially has a remarkable effect on treating children amblyopia, and has practical application and promotion value.

Description

technical field [0001] The invention specifically relates to a pharmaceutical composition for treating amblyopia. Background technique [0002] Amblyopia is no organic lesion in the eye, and the corrected visual acuity is less than 0.9. It is a common clinical eye disease in children. It usually starts in infants and young children. Appropriate visual stimuli can affect visual development and cause visual dysfunction, mainly manifested as low vision and binocular single vision dysfunction. [0003] At present, western medicine is the main method for treating amblyopia, and the medicines include levodopa and citicoline used in clinic. The side effects of dopamine on adults are very clear. Patients have adverse reactions such as nausea and vomiting, loss of appetite, abdominal distension, palpitation, dizziness, etc., and the side effects are even worse for children after long-term use. Citicoline may induce seizures, so seek Chinese medicine treatment Amblyopia in children ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61P27/10
CPCA61K36/704A61K36/64A61K36/804A61K36/815A61K36/39A61K36/43A61K36/884A61K36/537A61K36/236A61K36/752A61K9/0056A61P27/10A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00
Inventor 李希夏红冯建安黄嫣
Owner 四川省中医药科学院中医研究所
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