Fluorescent probe for detecting activity of acetylcholin esterase as well as synthesis method and application of fluorescent probe
An acetylcholinesterase and fluorescent probe technology, which is applied in the field of acetylcholinesterase activity detection, can solve the problems of low sensitivity, false positive effect and poor precision, and achieves the effect of high sensitivity
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[0052] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
[0053] The embodiment of the present invention discloses a MnO-based 2 Electrostatic interactions between nanosheets and PBI-DM, and a new method for detecting AChE activity based on the fluorescence spectral features of PBI during the aggregation-dispersion process, and provided the probe PBI-DM@MnO 2 The synthesis method and application of NS not only realize the quantitative detection of AChE in the aqueous phase, avoid the interference of some other thiol...
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