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Segmented encoding dual-core synchronous magnetic resonance imaging method

A technology of magnetic resonance imaging and segmentation coding, which is applied in the direction of using nuclear magnetic resonance imaging system for measurement, magnetic resonance measurement, measurement of magnetic variables, etc. Large differences, etc., to achieve the effect of consistent image resolution

Active Publication Date: 2019-12-24
WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
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Problems solved by technology

[0014] In the process of dual-nuclear simultaneous magnetic resonance imaging, the applied gradient acts on two nuclides at the same time. However, the magnetic spin ratio of different nuclides is an inherent property of the nucleus, and the difference is large. According to the formula (1)(4)(5) It is easy to know that for different nuclides, the same gradient is applied, and the slice thickness and FOV corresponding to the collected signals are different, resulting in different image sizes and resolutions, which is not conducive to the registration and comparison of images of different nuclides.

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[0055] In order to facilitate those of ordinary skill in the art to understand and implement the present invention, the present invention will be described in further detail below in conjunction with the examples. It should be understood that the implementation examples described here are only used to illustrate and explain the present invention, and are not intended to limit the present invention.

[0056] Loaded on the console of an MRI system that supports two or more channels of simultaneous transmission and reception such as figure 1 The pulse sequence shown; where the two transmit channels and the two receive channels correspond to core 1 and core 2, respectively.

[0057] A dual-nuclear synchronous magnetic resonance imaging method for segment encoding, comprising the following steps:

[0058] Step 1. Set the inspection area FOV (Field of View), layer thickness Th, and sampling matrix [M N];

[0059] Among them, M is the number of sampling points, N is the number of en...

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Abstract

The invention discloses a segmented encoding dual-core synchronous magnetic resonance imaging method. The segmented encoding dual-core synchronous magnetic resonance imaging method comprises the stepsthat an inspection region, a layer thickness and a sampling matrix are set; in a phase-encoding gradient channel GP, a first phase-encoding gradient is first applied, a second phase-encoding gradientis applied after the acquisition of a nuclear 2 magnetic resonance signal is completed, the intensity of the first phase of the phase-encoding gradient is the phase-encoding gradient array multipliedby gamma1 / gamma2, the intensity of the second phase-encoding gradient is |1-gamma1 / gamma2|*Gp, and if gamma1 is greater than gamma2, the second phase-encoding gradient is applied in the opposite direction; otherwise the second phase-encoding gradient is applied in the same direction as the first phase-encoding gradient. The reconstructed images of the two nuclides have the same resolution and one-to-one correspondence of pixel positions. The accurate registration of different nuclide images obtained by simultaneous imaging of the two nuclides is realized, and the problems of different nuclidelayer thicknesses and large differences in FOV are solved.

Description

technical field [0001] The invention relates to the technical field of magnetic resonance imaging, in particular to a dual-nuclear synchronous magnetic resonance imaging method for segment encoding. Background technique [0002] Magnetic resonance imaging (MRI) has been widely used in preclinical research and medical diagnosis. Water exists extensively and densely in organisms, and hydrogen nuclei have high NMR sensitivity, making them the preferred nuclei for imaging of organisms. However, for the observation of life activities and the development of diseases, one of the most basic and important physiological activities is metabolism. Proton nuclei can provide little metabolic information, and sodium ( 23 Na), phosphorus ( 31 P), oxygen ( 17 Nuclei such as O) are directly involved in metabolic activities; in addition, exogenous fluorine ( 19 F) Nanoprobes can obtain molecular target information, which can be used to locate the location of lesions, etc. Therefore, with t...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/055G01R33/44G01R33/48G01R33/58
CPCA61B5/055G01R33/446G01R33/48G01R33/583
Inventor 刘朝阳杨春升陈俊飞陈黎张震冯继文陈方鲍庆嘉
Owner WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
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