Biosafety Transit Chamber for Fluorescent Imaging of Live Animals

Abstract

The invention discloses a biosafety transfer bin used for living animal fluorescence imaging. The bin comprises a transfer outer bin, a transfer inner bin, a biological protection filter system and anegative pressure maintaining system, wherein the transfer inner bin, the biological protection filter system and the negative pressure maintaining system are arranged in the transfer outer bin, the transfer inner bin is used for placing a living animal, the biological protection filter system is used for filtering the air entering in and out of the transfer inner bin, and the negative pressure maintaining system is used for maintaining the interior of the transfer inner bin in the negative pressure environment. According to the biosafety transfer bin used for living animal fluorescence imaging, animals in the P3 level biosafety experiment chamber can be safely carried to a common experiment chamber to be further detected, due to the fact that many precision devices cannot be mounted in the P3 level experiment chamber, the bin develops the detection projects of living animals carrying out high risk of viruses, the bin is equivalent to the small movable P3 level experiment chamber, andthe more portable means is provided for transfer of the living animals with the viruses in the different regions.

Description

technical field [0001] The invention relates to the technical field of biological safety protection, in particular to a biological safety transfer chamber for fluorescent imaging of living animals. Background technique [0002] Biosafety laboratories are essential experimental conditions for the study of human infectious disease viruses. When studying active viruses, the effective protection of researchers and the surrounding environment is the basis of research and the basic guarantee for scientific research. Therefore, according to the nature and degree of hazard of the research object, the biosafety level (BSL) is divided into four levels, corresponding to pathogenic microorganisms with different degrees of biological danger, among which biosafety level three laboratories (BSL-3 or P3) and Biosafety level four laboratories (BSL-4 or P4) are called high-level biosafety laboratories. Due to the difficulty, high construction cost, and high technical requirements for the co...

AI Technical Summary

Problems solved by technology

The whole process of the experiment is closed and sealed to the outside, and the internal negative pressure system ensures that the aerosol will not leak, and high-efficiency filtration and disinfection are carried out at the air outlet, which can achieve basic biological safety protection, but the system cannot be equipped with large instruments, and can only carry out molecular or cell level experiments

In addition, there are also aerosol exposure systems for virus infection animal experiments on the market, some of which have corresponding biosafety protection devices, and some are small in size and can be placed in biosafety cabinets in biosafety laboratories. Non-precision instrument, simple structure, durable parts, low environmental requirements

In the biosafety market, most instruments only meet the needs of ordinary basic experiments, and there is basically no development and sale of high-precision instruments.

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