Traditional Chinese medicine composition for treatment of gouty arthritis and preparation method and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treatment of gouty arthritis and a preparation method and an application thereof. The traditional Chinese medicine composition consists of the following raw material medicines in parts by weight: 5-8 parts by weight of photiniae folia, 10-15 parts by weight of lignum pini nodi, 20-25 parts by weight of leaves of paniculate microcos, 20-25 parts by weight of flos cleistocalycis, 6-9 parts of herba lycopodii, 5-8 parts of root of mountain spicy tree, 5-7 parts of semen aesculi, and 5-8 parts of obscured homalomena rhizome. The traditional Chinese medicine composition has the functions of dispelling wind and clearing heat, removing dampness and relieving pain, regulating qi and dredging collaterals. Animal experimental results show that the traditional Chinese medicine composition can improve the degree of toe joint swelling and the arthritis index of gouty arthritis mice, and also improve the immune organ visceral index and antioxidant ability of the gouty arthritis mice without side effects. A new technical means is provided for treating gouty arthritis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its preparation method and application, in particular to a traditional Chinese medicine composition for treating gouty arthritis and its preparation method and application. The invention belongs to the technical field of traditional Chinese medicine. Background technique [0002] Gouty arthritis is one of the clinically common diseases (Higashino T, Matsuo H, Okada Y, et al. A common variant of MAF / c-MAF, transcriptional factorgene in the kidney, is associated with gout susceptibility[J]. Hum Cell, 2018, 31(1): 10-13.), it is mainly due to the combined effects of genetic factors, environmental factors, mental factors and other factors, which cause abnormal purine metabolism and lead to urate deposition In the joint capsule, synovial bursa, cartilage and other parts of the ankle joint and its foot joint, there will be aseptic inflammatory reaction in the damaged part, including red...

AI Technical Summary

Problems solved by technology

Data show that gouty arthritis is mostly due to abnormal purine metabolism in the body, resulting in excessive production of uric acid in the body or decreased excretion of uric acid due to poor kidney function, causing urate crystals to deposit in places with poor blood circulation system, such as The poor blood supply of joints and their surrounding tissues is conducive to the deposition of urate crystals. The deposition of urate crystals will stimulate aseptic inflammatory reactions in the joints and their surrounding tissues, which will eventually affect the basic functions of the joints

Images