Blood leukocyte segmentation method based on adaptive histogram threshold value and contour detection

A technology of contour detection and white blood cells, which is applied in the field of image processing, can solve the problem that the segmentation accuracy needs to be further improved, and achieve the effect of improving the segmentation accuracy

Active Publication Date: 2019-08-13
江苏谷梵智能科技有限公司
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Problems solved by technology

[0006] The segmentation accuracy of existing blood leukocyte image segmentation methods needs to be further improved

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  • Blood leukocyte segmentation method based on adaptive histogram threshold value and contour detection
  • Blood leukocyte segmentation method based on adaptive histogram threshold value and contour detection
  • Blood leukocyte segmentation method based on adaptive histogram threshold value and contour detection

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Embodiment Construction

[0056] The technical solution of the present invention will be specifically described below in conjunction with the accompanying drawings.

[0057] The present invention provides a blood white blood cell segmentation method based on adaptive histogram threshold and contour detection. First, the contrast of white blood cell nuclei is enhanced by combining color components, and then the rough segmentation of cell nuclei is realized by using the adaptive histogram thresholding method to locate white blood cells. , clip the sub-image where it is located; then, use the color prior to remove the background of each sub-image to obtain the white blood cell segmentation result, and use the adaptive histogram thresholding method to segment the sub-image again to achieve fine segmentation of the nucleus; finally use the white blood cell segmentation result to subtract The result of the segmentation of the nucleus is the result of the segmentation of the cytoplasm.

[0058] The implementa...

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Abstract

The invention relates to a blood leukocyte segmentation method based on an adaptive histogram threshold value and contour detection. The method comprises the following steps: firstly, enhancing the contrast ratio of cell nuclei through color component combination, and performing coarse segmentation on the cell nuclei by utilizing an adaptive histogram threshold technology to realize leukocyte localization; then, sequentially removing an image background and red blood cells by using the color prior information, and then executing edge detection to obtain a maximum connected component as an initial white blood cell contour; and finally, using image filling and morphological operation to realize extraction of a leukocyte region, so that a cytoplasm segmentation result is obtained. Experimental results on standard and rapid staining leukocyte image data sets prove that the method provided by the invention improves the leukocyte segmentation precision under two preparation conditions.

Description

technical field [0001] The invention belongs to the technical field of image processing, and is used for segmenting leukocytes in blood cell images collected in blood routine examinations, in particular to a blood leukocyte segmentation method based on adaptive histogram threshold and contour detection. Background technique [0002] Blood routine examination is a common item in human health testing. An important part of blood routine examination is the differential count and abnormal morphology analysis of white blood cells. At present, domestic hospitals usually use a blood cell analyzer based on the electrical impedance method (physical method) plus the flow analysis method (physical-chemical method) to perform differential counting of blood cells. Differential counting and morphological analysis of white blood cells in blood smears are of great significance in the diagnosis of leukemia and other blood diseases. When the blood cell count results are abnormal or the atten...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/136G06T7/13G06T7/194G06T5/00
CPCG06T7/136G06T7/13G06T7/194G06T2207/10024G06T2207/20032G06T2207/30004G06T5/70G06V20/69
Inventor 李佐勇周小根胡锦美赖桃桃周常恩刘伟霞
Owner 江苏谷梵智能科技有限公司
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