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Compound lantana camara L. plant extract and preparation method as well as application

A plant extract and extract technology, applied in the direction of plant raw materials, plant/algae/fungus/moss components, drug combinations, etc., can solve problems such as easy drug resistance

Pending Publication Date: 2019-08-02
GUANGXI UNIV FOR NATITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs act quickly, but have various adverse reactions such as drowsiness, thirst, retching, nausea, etc. Long-term use of these drugs is also prone to drug resistance

Method used

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  • Compound lantana camara L. plant extract and preparation method as well as application
  • Compound lantana camara L. plant extract and preparation method as well as application
  • Compound lantana camara L. plant extract and preparation method as well as application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 preparation of compound five-color plum plant extract

[0027] Weigh the leaves and thin stems of the five-color plum and place them in an extraction container, add 5 times the amount of botanical medicine 95% ethanol, heat and reflux for extraction at a constant temperature of 80°C for 2 hours, filter to obtain the extract, add 10 times 95% ethanol to the medicinal residues, Reflux extraction at a constant temperature of 80°C for 1 hour, filter to obtain the secondary extract, combine the two extracts, depigment with activated carbon, concentrate the filtrate into an extract, freeze-dry at low temperature, and finally obtain the five-color plum extract.

[0028] Weigh the white fresh bark and place it in an extraction container, add 5 times the weight of the botanical medicine with 75% ethanol, reflux and extract at a constant temperature of 85°C for 2 hours, filter to obtain the extract, continue to add 10 times the amount of 75% ethanol to the dregs, and ...

Embodiment 2

[0031] Embodiment 2 preparation of compound five-color plum plant extract

[0032] Weigh the leaves and thin stems of the five-color plum and place them in an extraction container, add 5 times the amount of botanical medicine 95% ethanol, heat and reflux for extraction at a constant temperature of 80°C for 2 hours, filter to obtain the extract, add 10 times 95% ethanol to the medicinal residues, Reflux extraction at a constant temperature of 80°C for 1 hour, filter to obtain the secondary extract, combine the two extracts, depigment with activated carbon, concentrate the filtrate into an extract, freeze-dry at low temperature, and finally obtain the five-color plum extract.

[0033] Weigh the white fresh bark and place it in an extraction container, add 5 times the weight of the botanical medicine with 75% ethanol, reflux and extract at a constant temperature of 85°C for 2 hours, filter to obtain the extract, continue to add 10 times the amount of 75% ethanol to the dregs, and ...

Embodiment 3

[0036] Embodiment 3 preparation of compound five-color plum antiallergic spray film

[0037] Formula (mass percentage): 8% of five-color plum extract, 6% of white fresh skin extract, 6% of Senecio extract, 5% of polyvinylpyrrolidone, 0.4% of hypromellose, 0.3% of glycerin, 60% of ethanol, 0.2% borneol, 1% menthol, and the balance is water. Among them, the five-color plum extract, the white fresh bark extract, and the Senecio extract were prepared with reference to Example 1.

[0038] Preparation method:

[0039] (1) Add polyvinylpyrrolidone to the ethanol solution, then add five-color plum extract, white fresh bark extract, and Senecio extract according to the formula, and mix well to obtain solution A;

[0040] (2) Dissolving hypromellose in water, and adding to solution A and stirring evenly;

[0041] (3) Add menthol, borneol, glycerin and water into the mixed solution obtained in step (2) to obtain the anti-allergic spray film.

[0042] In order to prove the effect of the...

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PUM

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Abstract

The invention discloses a compound lantana camara L. traditional Chinese medicine, prepared from antana camara L., cortex dictamni and climbing groundsel herb. Based on this, a compound lantana camaraL. plant extract and a preparation method thereof are developed. The compound lantana camara L. plant extract is prepared from a lantana camara L. extract, a cortex dictamni extract and a climbing groundsel herb extract. The extracts are all ethanol extract. From this, an antiallergic spraying agent is researched and prepared. Evaluations of a hyaluronidase inhibition experiment, a dextran-induced mouse skin pruritus experiment and a xylene-induced mouse ear swelling experiment prove that the compound lantana camara L. traditional Chinese medicine / plant extract and the antiallergic spraying agent have excellent antiallergic effects. The used three extracts come from natural plants, are mild, safe and irritation-free, are stable in quality and low in cost, and have a broad market prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a compound five-color plum plant extract and a preparation method and application thereof. Background technique [0002] Allergy is a sudden, rapid and abnormal physiological reaction. The clinical manifestations are flushing of the skin, itching of hands and feet, etc. In severe cases, upper respiratory tract symptoms such as mouth, tongue, and throat edema, coughing, arrhythmia, and even respiratory arrest appear in the lower respiratory tract. Serious damage to the human body. At present, the drugs for the treatment of allergic reactions mainly include chlorpheniramine maleate, desloratadine, sodium cromoglycate, corticosteroids, and trypsin. These drugs act quickly, but have various adverse reactions such as drowsiness, unbearable thirst, retching, and nausea. Long-term use of these drugs is also prone to drug resistance. Natural medicines ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61K9/70A61K47/32A61K47/38A61P37/08A61P17/04A61P29/00A61K8/9789A61K8/81A61K8/73A61K8/02A61Q19/00
CPCA61K8/0208A61K8/731A61K8/8176A61K9/7015A61K36/28A61K36/75A61K36/85A61K47/32A61K47/38A61K2236/333A61K2236/39A61K2236/51A61K2800/782A61Q19/005A61K8/9789A61P17/04A61P29/00A61P37/08A61K2300/00
Inventor 杨立芳韦炎冶姜明国石松标刘聪陈林梦姜昱
Owner GUANGXI UNIV FOR NATITIES
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