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A composition with whitening effect and its preparation method and application

A technology of composition and efficacy, which is applied in the field of composition with whitening effect and its preparation, can solve the problems of single whitening additive mechanism and lack of comprehensive application of multiple mechanisms, and achieve the benefits of large-scale industrial production and facial pigmentation. Effect of reduction and high extraction rate

Active Publication Date: 2022-02-11
SHANGHAI JAKA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the mechanism of whitening additives used in cosmetic products is relatively single, mainly to inhibit the activity of tyrosinase, and lacks the comprehensive application of multiple mechanisms. In order to develop whitening cosmetics with more outstanding efficacy, the comprehensive application of various mechanisms is required To better achieve the purpose of whitening the skin

Method used

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  • A composition with whitening effect and its preparation method and application
  • A composition with whitening effect and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] (1) Weigh the raw materials according to the mass ratio in Table 1: 100g of Cistanche, 100g of Poria, 100g of Astragalus, 100g of Angelica sinensis, 100g of Chuanxiong; respectively use 5 times the amount of Cistanche, Poria and Astragalus [solution volume (ml): weight of medicinal materials ( g)] extraction with an aqueous ethanol solution with a volume concentration of 100%, and an extraction temperature of 30° C.; the extraction times are 3 times, and the extracts are combined to obtain the extract A, and the medicinal residues are combined to obtain the medicinal residues to be recovered;

[0035] (2) adding water to decoct the to-be-recovered medicinal residues obtained in step (1), filtering to obtain a filtrate, concentrating the filtrate and centrifugal filtration to obtain a clarified solution, adding an aqueous ethanol solution with a volume concentration of 95% to the clarified solution, and leaving it to stand overnight for three times. Daily centrifugal filt...

Embodiment 2

[0040] (1) Weigh the raw materials according to the mass ratio in Table 1: 5g of Cistanche, 100g of Poria, 5g of Astragalus, 5g of Angelica, 5g of Chuanxiong; respectively use 20 times the amount of Cistanche, Poria, and Astragalus [solution volume (ml): medicinal material weight ( g)] extraction with an ethanol aqueous solution with a volume concentration of 50%, the extraction temperature is 80°C; the number of extractions is 1 time, the extracts are combined to obtain the extract A, and the dregs are combined to obtain the dregs to be recovered;

[0041] (2) Decoct the medicinal dregs to be recovered obtained in step (1) with water, filter to obtain a filtrate, concentrate the filtrate and centrifugally filter to obtain a clear solution, add an aqueous ethanol solution with a volume concentration of 95% to the clear solution, let stand overnight, and Centrifugal filtration every day to obtain the crude polysaccharide extract of Cistanche deserticola, Poria cocos and Astragalus...

Embodiment 3

[0046] (1) Weigh the raw materials according to the mass ratio in Table 1: 50g of Cistanche, 75g of Poria, 70g of Astragalus, 75g of Angelica, and 60g of Chuanxiong; g)] extraction with an ethanol aqueous solution with a volume concentration of 80%, the extraction temperature is 50°C; the number of extractions is 2 times, the extract is combined to obtain the extract A, and the dregs are combined to obtain the dregs to be recovered;

[0047] (2) Decoct the medicinal dregs to be recovered obtained in step (1) with water, filter to obtain a filtrate, concentrate the filtrate and centrifugally filter to obtain a clear solution, add an aqueous ethanol solution with a volume concentration of 95% to the clear solution, let stand overnight, and Centrifugal filtration every day to obtain the crude polysaccharide extract of Cistanche deserticola, Poria cocos and Astragalus membranaceus, which is recorded as extract B;

[0048] (3) Extract Angelica and Rhizoma Chuanxiong with 15 times t...

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Abstract

The invention relates to the technical field of cosmetics, in particular to a composition with whitening effect and its preparation method and application. Based on the dry weight of medicinal materials, the composition with whitening effect is made of the following raw materials in parts by weight: 1-20 parts of Cistanche, 1-20 parts of Poria cocos, 1-20 parts of Astragalus, 1-20 parts of Angelica sinensis, 1-20 parts of Rhizoma Chuanxiong. ~20 servings. The composition of the present invention achieves more powerful effects such as skin whitening and facial stain reduction through the synergy and synergy of the four components of Cistanche deserticola extract, Poria cocos extract, Astragalus extract, Angelica extract and Chuanxiong extract. The whitening effect; the preparation process conditions are mild, the extraction rate is high, there is no special requirement for equipment, the preparation cost is low, and it is beneficial to large-scale industrial production.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a composition with a whitening effect, a preparation method and an application thereof. Background technique [0002] Asian women have always pursued fair skin. However, due to the fast pace of work, high psychological pressure, endocrine disorders, environmental pollution and other internal and external factors, the skin will also appear dull, pigmented and other phenomena, so whitening is one of the most important themes of skin care. [0003] Commonly referred to as melanin mainly refers to superior melanin and pheomelanin. Modern aesthetic medicine shows that melanin is formed through a series of oxidation reactions: the participation of three enzymes in different stages: tyrosinase, dopachrome tautomerase, and 5,6-dihydroxyindole carboxylic acid oxidase At the same time, under the catalysis of cysteine ​​or glutathione, the above reaction process The intermediate produc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9728A61K8/9789A61Q19/02A61Q17/04
Inventor 杨雅迪卢伊娜
Owner SHANGHAI JAKA BIOTECH CO LTD
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