Dry powder inhaler with blister bursting device

A dry powder inhaler and blister technology, which is applied in the field of blister opening devices, can solve the problems of obstructing airflow and large foil flaps, and achieves the effect of increasing the discharged dose

Active Publication Date: 2019-01-04
VECTURA DELIVERY DEVICES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the large opening in the blister means the foil flap is large and therefore more likely to trap powder and impede airflow

Method used

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  • Dry powder inhaler with blister bursting device
  • Dry powder inhaler with blister bursting device
  • Dry powder inhaler with blister bursting device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0046] first reference Figure 1 to Figure 4 , the multi-dose dry powder inhaler is generally represented by 10. The inhaler 10 includes a housing 12 defining a chamber 14, a strip of blisters 16 within the chamber 14, a mouthpiece 18 for the user to inhale a dose of medicament, an actuator, and each blister is opened in response to movement of the actuator. The indexing system for moving the cover to the blister opening position 20 and the blister opening device in turn.

[0047] The chamber 14 is basically divided into two compartments, separated by a movable wall 22 . Such a wall 22 has been described in the applicant's own WO 2012 / 069854. Before using the inhaler 10 for the first time, an unused roll of blister strip 16 is stored in the first compartment 24 . As the blister strip 16 is advanced through the indexing system, the blister strip 16 unrolls and advances toward the blister open position 20 . Subsequent indexing movements cause the opened (ie used) portion of ...

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PUM

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Abstract

A multi-dose dry powder inhaler with a blister folding device is provided. The inhaler comprises a housing containing a blister strip, and a blister opening device. The blister strip comprises a plurality of individual blisters, each blister containing a dose of medicament for inhalation by a user. The blister opening device comprising a blister support element for supporting one of said blisters,and a blister folding element co-operable with the blister support element, the blister folding element and the blister support element being movable relative to each other between a first position,permitting movement of said blister into or onto the blister support element, and a second, burst, position in which the blister folding element has co-operated with the blister support element. Movement from the first position to the second position causes two spaced apart portions of said blister to each fold relative to the remainder of the blister to produce two spaced apart openings, each opening extending along the circumference of the blister bowl, beginning and terminating at points located on the fold line No piercing of the blister at any stage is required.

Description

technical field [0001] The present invention relates to a blister opening device for a multi-dose dry powder inhalation device. In particular, the present invention relates to a blister bursting device for bursting or rupturing to open the lid of a blister containing a single dose of medicament for inhalation by a user of an inhalation device. Background technique [0002] Oral or nasal administration using an inhalation device is a particularly attractive method of administration because these devices are relatively easy for the patient to use discreetly and openly. In addition to administering drugs to treat localized airway diseases and other respiratory problems, these drug delivery methods are used to deliver drugs through the lungs into the bloodstream, avoiding the need for subcutaneous injections. [0003] Dry powder formulations are typically prepackaged in blisters, each containing a precisely and consistently measured dose of powder. In addition to protecting th...

Claims

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Application Information

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IPC IPC(8): A61M11/00A61M15/00
CPCA61M11/00A61M15/0031A61M15/0041A61M15/0051A61M15/0021A61M15/0056A61M2202/064
Inventor P.威尔森R.克拉克L.麦吉尼斯
Owner VECTURA DELIVERY DEVICES
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