Cell nucleus segmentation method and system for fluorescence in situ hybridization images
A technology of fluorescence in situ hybridization and cell nucleus, which is applied in the field of cell nucleus segmentation method and system of fluorescence in situ hybridization image, which can solve the problems of blurred nucleus edge and cell adhesion, so as to improve the quality of segmentation, improve over-segmentation, and improve the accuracy rate Effect
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[0041] The present invention will be described in further detail below in conjunction with the accompanying drawings and embodiments, but these embodiments should not be construed as limiting the present invention.
[0042] The present invention proposes a flow process of a cell nucleus segmentation method for fluorescence in situ hybridization images as follows: figure 1 Shown, is for a given FISH image of breast cancer (such as figure 2 shown) to find the process of the nucleus region, the specific steps include:
[0043] 1) The preprocessed FISH image (such as image 3As shown), the pixel value of each pixel of the red, green, and blue three-channel images in the image is reduced by adt_value to ensure that any position of the image is still greater than or equal to 0 after the reduction, and the overall displacement of the image is realized; the value range of adt_value is [2050 ] pixels. Collect the red channel and green channel in the three-channel image where the pi...
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