Cancer cell HER2 gene amplification analyzing method and system
A technology of gene amplification and analysis method, applied in the field of HER2 gene amplification analysis method and system of cancer cells, can solve the problems of low recognition rate of HER2 gene amplification and blurred edge of cell nucleus, etc., so as to improve segmentation quality and reduce work quantity, and the effect of improving the accuracy
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[0054] The present invention will be described in further detail below in conjunction with the accompanying drawings and embodiments, but these embodiments should not be construed as limiting the present invention.
[0055] Such as figure 1 As shown, a kind of cancer cell HER2 gene amplification analysis method proposed by the present invention, the specific steps include:
[0056] 1) Perform red dot clustering analysis on the red channel image of the FISH image. If the total number of single red dot clusters exceeds the set value, it is directly determined as HER2 gene amplification, and go to step 7), otherwise go to step 2).
[0057] The analysis method of clustering red dots is:
[0058] 11) separate the red channel of the input FISH image to obtain the red channel image;
[0059] 12) Perform morphological operations on the red channel image, use structural elements to perform top-hat operations on the red channel, and the radius of the structural elements is 80, elimina...
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