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Method for screening disease resistance breeding of animals

A technology for animals and cases, applied in the direction of biochemical equipment and methods, microbe measurement/inspection, etc., can solve the problems of incomplete control and elimination of infectious diseases, and achieve the effect of low cost, easy control, and good operability

Inactive Publication Date: 2018-11-20
XINJIANG ACADEMY OF AGRI & RECLAMATION SCI
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Problems solved by technology

The development of modern epidemic prevention technology has played an important role in prevention and control to a large extent, but it has not completely controlled and eliminated the epidemic of infectious diseases

Method used

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Embodiment Construction

[0014] The technical solutions of the present invention will be further described in detail below in conjunction with specific embodiments.

[0015] A method for screening animal disease-resistant breeding, characterized in that it comprises the following steps:

[0016] Comparing genomic hybridization chips to detect differences in genome copy number variation between diseased and disease-resistant animal groups, if there is an increase or decrease in genome copy number variation between diseased animals and disease-resistant animals, combined with statistical analysis, a preliminary judgment can be made in the Genes within the genome copy number variation segment are associated with disease resistance, and animals associated with desired traits are selected for breeding.

[0017] The specific steps for comparing genome hybridization chips to detect differences in genome copy number variation between a diseased animal population and a disease-resistant animal population are: ...

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Abstract

The invention discloses a method for screening disease resistance breeding of animals and belongs to the technical field of disease resistance breeding of the animals. Genome copy number variation differences of affected animal individuals and disease-resistant animal individuals are detected by a comparative genomic hybridization chip, if the genome copy number of affected animals is more or lessthan that of disease-resistant animals, the condition that genes in genome copy number variation sections are related to disease resistance can be judged preliminarily, and the related animals havingrequired characteristics can be selected for breeding. The method for screening disease resistance breeding of the animals has the characteristics that the method is simple and convenient to operate,low in cost and high in efficiency, and the method is suitable for popularization and application.

Description

technical field [0001] The invention belongs to the technical field of animal disease-resistant breeding and relates to a method for screening animal disease-resistant breeding. Background technique [0002] During the growth and development of animals, they are often attacked by various pathogens, showing disease resistance or susceptibility. Animal disease is the enemy that affects the production of modern livestock and poultry industry. Diseases not only seriously threaten the health of animals, but also cause huge economic losses to the livestock and poultry industry. Animal infectious diseases, especially viral infectious diseases, are the primary prevention and control targets for animal health threats. The development of modern epidemic prevention technology has played an important role in prevention and control to a large extent, but it has not completely controlled and eliminated the prevalence of infectious diseases. In the long run, the use of genetic methods to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/6809
CPCC12Q1/6809C12Q2537/16C12Q2563/107
Inventor 石国庆万鹏程代蓉管峰甘尚泉杨永林倪建宏杨杰李良缘
Owner XINJIANG ACADEMY OF AGRI & RECLAMATION SCI
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