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Traditional Chinese medicine composition for treating myotonia type Parkinson's disease and preparation method thereof

A technology for Parkinson's disease and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of tonic Parkinson's disease, and can solve problems such as lack of effective therapeutic drugs

Active Publication Date: 2018-09-11
JIAMUSI UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is a lack of effective therapeutic drugs, and there is an urgent need for effective and safe drugs for the treatment of Parkinson's disease in the market

Method used

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  • Traditional Chinese medicine composition for treating myotonia type Parkinson's disease and preparation method thereof
  • Traditional Chinese medicine composition for treating myotonia type Parkinson's disease and preparation method thereof
  • Traditional Chinese medicine composition for treating myotonia type Parkinson's disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Take Acanthopanax 10kg, Radix Paeoniae Alba 10kg, Radix Astragali 5kg, Asparagus 5kg, add water to decoct twice, add 240kg of water for the first time, decoct for 3 hours, add 180kg of water for the second time, decoct for 2 hours, filter, and combine the filtrate , concentrated in vacuo, dried under reduced pressure to obtain dry cream powder, added 2kg of starch, 1kg of dextrin, wet granulated with water, dried at 50°C, granulated, added 0.05kg of magnesium stearate, mixed, pressed into tablets, each tablet 0.4 g, made into tablets.

specific Embodiment 2

[0017] Take Acanthopanax 10kg, Radix Paeoniae Alba 10kg, Radix Astragali 5kg, Asparagus 5kg, add water to decoct twice, add 240kg of water for the first time, decoct for 3 hours, add 180kg of water for the second time, decoct for 2 hours, filter, and combine the filtrate , concentrated in vacuo, dried under reduced pressure to obtain dry cream powder, added starch 1kg, talcum powder 0.5kg, magnesium stearate 0.04kg, mixed evenly, packed into No. 1 capsule, each 0.3g, and made into capsules.

Embodiment 3

[0019] Take Acanthopanax 10kg, Radix Paeoniae Alba 10kg, Radix Astragali 5kg, Asparagus 5kg, add water to decoct twice, add 240kg of water for the first time, decoct for 3 hours, add 180kg of water for the second time, decoct for 2 hours, filter, and combine the filtrate , concentrated in vacuum, added purified water to 20kg, sterilized by high-pressure steam, packed into oral liquid bottles, 10ml per bottle, to make oral liquid.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating myotonia type Parkinson's disease and a preparation method thereof. The composition is characterized in that radix et caulis acanthopanacis senticosi, radix paeoniae alba, radix astragali, radix asparagi are taken, decoction is carried out after water is added, then filtration, concentration and drying are carried out,and pharmaceutically acceptable ingredients are added to prepare a troche, a capsule, an oral liquid and a granule. The traditional Chinese medicine composition is used for treating the myotonia typeParkinson's disease, compared with a chemotherapeutic drug and traditional Chinese medicine therapeutic drug sold in the market, the therapeutic effect is obviously improved, and a promising result is obtained.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating ankylosing Parkinson's disease and a preparation method thereof. Background technique [0002] Parkinson's disease is a common neurodegenerative disease in middle-aged and elderly people, and it is also the most common extrapyramidal system disease in middle-aged and elderly people. It is divided into tonic type and tremor type. The main clinical feature of myotonic Parkinson's disease is that the muscle tension of both the stimulatory muscle and the antagonistic muscle is increased. When the joint is passively moved, the increased muscle tension is always consistent and the resistance is uniform, which is called "lead pipe-like rigidity". ", the clinical manifestations are slowness of movement and reduction, unstable posture, etc. as the main features. The traditional Chinese medical science thinks that the pat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8965A61P25/16
CPCA61K36/8965A61P25/16A61K36/254A61K36/481A61K36/65A61K36/71A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 孙长海李野杨玉婷方衡
Owner JIAMUSI UNIVERSITY
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