Automatic sampling device of dissolution tester

Abstract

The invention relates to an automatic sampling device of a dissolution tester. The automatic sampling device comprises a multi-channel valve group, wherein the multi-channel valve group comprises fivebranches; a power pump is connected with a public channel of the multi-channel valve group; a sampling needle is connected with the first branch of the multi-channel valve group; a dissolution cup isconnected with the second branch of the multi-channel valve group; a sample injection needle is connected with the third branch of the multi-channel valve group; a liquid supplementing groove is connected with the fourth branch of the multi-channel valve group through a liquid supplementing pipeline; the fifth branch of the multi-channel valve group is communicated with external air. According tothe automatic sampling device of the dissolution tester, provided by the invention, the power pump can be communicated with the corresponding pipeline under different conditions; in an automatic sampling process of a dissolution experiment, operation including automatic sampling, automatic liquid supplementing, automatic pipeline emptying, automatic pipeline washing and the like can be rapidly and accurately finished; sampling requirements of pharmacopeia on the dissolution experiment are met; accurate, reliable and efficient sampling is realized, and a condition that a sample is polluted byadjacent sampling points is avoided.

Description

technical field [0001] The invention relates to the related technical field of drug detection equipment, in particular to an automatic sampling device for a dissolution instrument. Background technique [0002] The sample sampling technology in the dissolution test process of tablets, capsules, and granules currently has certain defects in terms of synchronous sampling, sampling accuracy, automatic sampling positioning, and fluid replacement accuracy, which are mainly manifested in: [0003] 1. The sampling time error of manual sampling is relatively large, and synchronous sampling cannot be realized, and there is also a large error in the position of the sampling needle during manual sampling; [0004] 2. Automatic sampling, the sampling position cannot be automatically positioned, and the dead volume of the sampling pipeline leads to inaccurate sampling volume; [0005] 3. The automatic sampling process cannot completely empty the remaining samples in the pipeline, result...

AI Technical Summary

Problems solved by technology

[0003] 1. The sampling time error of manual sampling is relatively large, and synchronous sampling cannot be realized, and there is also a large error in the position of the sampling needle during manual sampling;

[0004] 2. Automatic sampling, the sampling position cannot be automatically positioned, and the dead volume of the sampling pipeline leads to inaccurate sampling volume;

[0005] 3. The automatic sampling process cannot completely empty the remaining samples in the pipeline, resulting in cross-infection of adjacent samples and inaccurate samples;

[0006] 4. Automatic sampling cannot automatically refill or the temperature of the replenished liquid cannot meet the requirements of the Pharmacopoeia

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