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A kind of pharmaceutical composition for hair and its preparation method and application

A composition and medicine technology, applied in the field of hair pharmaceutical composition and preparation thereof, can solve the problems of scalp atrophy, prone to rebound, no improvement of skin oiliness, etc., and achieve improvement of skin oiliness, convenient use, and good clinical application. Foreground effect

Active Publication Date: 2020-06-30
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the topical lotion for the treatment of scalp seborrheic dermatitis is mainly the anti-dandruff drug "Compound Ketoconazole Hair Lotion", which is mainly composed of ketoconazole and clobetasol propionate, and ketoconazole is an antifungal drug. , can effectively remove dandruff; clobetasol propionate is a glucocorticoid, which can quickly eliminate scalp itching, but topical glucocorticoids can only obtain short-term curative effect, and are prone to rebound phenomenon, and long-term use may lead to adverse reactions such as scalp atrophy , In addition, "compound ketoconazole hair lotion" does not involve in improving skin oiliness

Method used

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  • A kind of pharmaceutical composition for hair and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1 Preparation of the pharmaceutical composition of the present invention

[0035] 1. Raw materials: 15g of Senecio, 15g of cork, 30g of arborvitae leaves, 30g of licorice, 3g of borneol, 15g of Sophora flavescens, 15g of rhubarb, 10g of Glauber's salt, 10g of alum, 10g of mugwort leaf, 10g of xanthium, 30g of Cnidium.

[0036] 2. Preparation method: weigh the bulk drug according to the above weight ratio;

[0037] ①Add 15 times the amount of medicinal materials, and boil the fire first, then simmer three times for 30 minutes each time. After boiling, filter the medicinal liquid with three layers of gauze and discard the medicinal residue;

[0038] ② Reduce the concentrated liquid medicine to 1 / 3 of the original liquid medicine;

[0039] ③ Glauber's salt and dry alum should not be decocted for a long time, and will be directly dissolved in the liquid after the liquid is filtered;

[0040] ④ Borneol is dissolved in 30ml of 75% alcohol and poured into the liquid after the liq...

Embodiment 2

[0044] Example 2 Preparation of the pharmaceutical composition of the present invention

[0045] 1. Raw materials: Senecio 20g, Cork 18g, Platycladus orientalis leaf 40g, Licorice 35g, Borneol 5g, Sophora flavescens 18g, Rhubarb 20g, Glauber's salt 12g, Alum 15g, Mugwort leaf 12g, Xanthium 15g, Cnidium 35g.

[0046] 2. Preparation method: weigh the bulk drug according to the above weight ratio; the same as in Example 1.

Embodiment 3

[0047] Example 3 Preparation of the pharmaceutical composition of the present invention

[0048] 1. Raw materials: Senecio 10g, Cork 12g, Platycladus orientalis leaves 20g, Licorice 25g, Borneol 2g, Sophora flavescens 12g, Rhubarb 10g, Glauber's salt 8g, Alum 5g, Mugwort 8g, Xanthium 5g, Cnidium 25g.

[0049] 2. Preparation method: weigh the bulk drug according to the above weight ratio; the same as in Example 1.

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Abstract

The invention discloses a pharmaceutical composition for hair as well as a preparation method and application of the pharmaceutical composition and belongs to the field of traditional Chinese medicines. The pharmaceutical composition is composed of the following raw medicinal materials in parts by weight: 10-20 parts of groundsel, 10-20 parts of cortex phellodendri, 20-40 parts of cacumen biotae,20-40 parts of liquorice, 2-5 parts of borneol, 10-20 parts of radix sophorae flavescentis, 10-20 parts of rheum officinale, 5-15 parts of mirabilite, 5-15 parts of dried alum, 5-15 parts of folium artemisiae argyi, 5-15 parts of cocklebur fruit and 20-40 parts of fructus cnidii. The pharmaceutical composition for hair disclosed by the invention can achieve effects of effectively removing dandruff, relieving itching, obviously improving greasy skin and retarding or preventing hair loss, and has non-specific anti-inflammatory action and exact clinical curative effects; and the pharmaceutical composition can be used for preparing medicines for treating scalp seborrheic dermatitis, alopecia seborrhoeica and scalp folliculitis. More importantly, the pharmaceutical composition for hair disclosed by the invention does not contain glucocorticoid and does not cause any adverse reaction due to long-term use.

Description

Technical field [0001] The invention belongs to the field of traditional Chinese medicine, and specifically relates to a hair medicine composition and a preparation method and application thereof. Background technique [0002] Scalp seborrheic dermatitis is a common chronic superficial and inflammatory skin disease. The skin lesions are manifested as scales on the basis of erythema, which can be accompanied by itching and greasy; seborrheic alopecia and genetics, androgen levels, seborrhea, etc. Related, hair loss is generally caused by seborrheic dermatitis. The symptoms are excessive oil secretion on the scalp and the hair feels greasy. [0003] Studies over the years have shown that seborrheic dermatitis mostly occurs in the developed parts of the sebaceous glands, and Malassezia furfur is a lipophagic microorganism. Seborrheic dermatitis may be related to the existence of Malassezia furfur, so it is anti-fungal Drug treatment of seborrheic dermatitis is one of the important tr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61P17/08A61P17/14A61P17/00A61P17/04A61P29/00A61K31/045A61K33/04A61K33/06
CPCA61K9/0014A61K31/045A61K33/04A61K33/06A61K36/14A61K36/234A61K36/28A61K36/282A61K36/484A61K36/489A61K36/708A61K36/756A61K2236/331A61K2236/39A61K2300/00
Inventor 李天浩
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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