Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A Haitian melon active peptide with hypoglycemic activity

A Haitian melon and hypoglycemic technology, applied in the field of Haitian melon active peptides, can solve problems such as lack of deep processing

Active Publication Date: 2021-04-09
LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI +1
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the development of Haitian melon is simply used as food, lack of deep processing

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Crush 100g of dried Haitian melon, add water to make a suspension, wherein the mass ratio of Haitian melon to water is 1:6; then add 2% trypsin and papain compound enzyme (1:1) for enzymatic hydrolysis, the enzymatic hydrolysis process A magnetic stirrer was used in the medium, the enzymolysis time was 4 hours, the temperature was 50°C, and the pH value was 7; after the enzymolysis, ethanol was added to precipitate the polysaccharide, and the supernatant was collected after centrifugation at 8000rpm for 20min, and the supernatant was filtered through 1000Da and 360Da membranes , collect the concentrated solution with a molecular weight of 360-1000, decolorize the concentrated solution with activated carbon, remove fishy smell, and spray dry to obtain 10.65g of Haitian melon polypeptide. Through multiple screening and evaluation methods such as α-amylase inhibitor screening model, α-glucosidase inhibitor screening model, DPP4 inhibitor screening model, and insulin secreti...

Embodiment 2

[0022] Crush 100g of dried Haitian melon, add water to make a suspension, wherein the mass ratio of Haitian melon to water is 1:6; then add 2% trypsin and papain (3:2) for enzymatic hydrolysis, the enzymatic hydrolysis process Use a magnetic stirrer in the medium, enzymolysis time 2h, temperature 50°C, pH value 7; after enzymolysis, add ethanol to precipitate polysaccharides, centrifuge at 8000rpm for 20min, take the supernatant, and filter the supernatant through 1000Da and 360Da membranes , collect the concentrated solution with a molecular weight of 360-1000, decolorize the concentrated solution with activated carbon, remove fishy smell, and spray dry to obtain 13.5g of Haitian melon polypeptide. Through multiple screening and evaluation methods such as α-amylase inhibitor screening model, α-glucosidase inhibitor screening model, DPP4 inhibitor screening model, and insulin secretion model of islet cells after high-glucose injury, the combination of trypsin and papain was det...

Embodiment 3

[0024] Crush 100g of dried Haitian melon, add water to make a suspension, wherein the mass ratio of Haitian melon to water is 1:6; then add 4% trypsin and papain compound enzyme (3:1) for enzymatic hydrolysis, the enzymatic hydrolysis process Use a magnetic stirrer in the medium, enzymolysis time 2h, temperature 50°C, pH value 7; after enzymolysis, add ethanol to precipitate polysaccharides, centrifuge at 8000rpm for 20min, take the supernatant, and filter the supernatant through 1000Da and 360Da membranes , collect the concentrated solution with a molecular weight of 360-1000, decolorize the concentrated solution with activated carbon, remove the smell, and spray dry to obtain 17.8g of Haitian melon polypeptide. Through multiple screening and evaluation methods such as α-amylase inhibitor screening model, α-glucosidase inhibitor screening model, DPP4 inhibitor screening model, and insulin secretion model of islet cells after high-glucose injury, the combination of trypsin and ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a Haitian melon active peptide with hypoglycemic activity, a method for preparing oral liquid by using Haitian melon hypoglycemic peptide, using Haitian melon as a raw material, and can prepare Haitian melon active polypeptide from Haitian melon, which is low in cost and environmentally friendly. Oral administration of the Haitian melon active polypeptide can assist in lowering blood sugar, and has the effect of assisting in lowering blood sugar. The Haitian melon hypoglycemic peptide can be used as an active ingredient to prepare oral liquids, and has a good market prospect. The method for preparing the oral liquid by using the Haitian melon hypoglycemic peptide has the advantages of simple preparation, good controllability, easy operation and implementation, easy industrialized large-scale production, and has broad application prospects and good economic benefits.

Description

technical field [0001] The invention belongs to the technical field of active substance development, and in particular relates to a Haitian melon active peptide with hypoglycemic activity and application thereof. Background technique [0002] Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to insulin secretion defect or insulin action disorder, mainly manifested as polydipsia, polydipsia, polyuria, polyphagia, fatigue, weight loss and other symptoms. Sustained high blood sugar and long-term metabolic disorders can lead to damage, dysfunction and failure of tissues and organs throughout the body, especially the eyes, kidneys, cardiovascular and nervous systems. At present, there are many hypoglycemic drugs approved for marketing, but all of them have strong side effects. Therefore, oral administration of food-derived oral liquids with hypoglycemic effect is a very effective method. [0003] Haitian melons are abundant in subtropical sandy sea area...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C12P21/06C07K1/34A23L33/18A23L33/00
CPCA23V2002/00A23L33/00A23L33/18C12P21/06A23V2200/328A23V2250/55
Inventor 邸多隆王宁丽裴栋魏鉴腾
Owner LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com