Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Fracture healing simulation method based on tissue oxygen environment and mechanical environment

A mechanical environment and fracture healing technology, applied in the field of biomedical engineering, can solve problems such as inability to achieve fixator optimization, fixator selection restrictions, and hindering treatment plans

Inactive Publication Date: 2018-01-19
HARBIN UNIV OF SCI & TECH
View PDF4 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] (1) The important influence of the oxygen environment on the proliferation and differentiation of cells in the tissue during the fracture healing process is not considered
[0005] (2) The current model cannot simulate different types of fracture healing in different parts of specific patients
[0006] (3) There are great restrictions on the selection of fixators. The existing model only simulates one fixation method, and cannot realize the optimization of fixators, which hinders doctors from providing better treatment options for patients.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Fracture healing simulation method based on tissue oxygen environment and mechanical environment
  • Fracture healing simulation method based on tissue oxygen environment and mechanical environment
  • Fracture healing simulation method based on tissue oxygen environment and mechanical environment

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0059] Specific implementation mode one: establish a three-dimensional geometric model of the fracture site;

[0060] The establishment process of the 3D geometric model of the fracture site is as follows:

[0061] (1) Multiple images in DICOM format obtained from medical imaging CT scans,

[0062] (2) Then import it into Mimics software for 3D reconstruction,

[0063] (3) Import the 3D reconstructed model into Geomagic software for smoothing and materialization operations to obtain a 3D geometric model of the fracture site;

specific Embodiment approach 2

[0064] Specific embodiment two: import the obtained geometric model into Hypermesh for grid division, and set up the finite element model of linear elastic bone and callus;

specific Embodiment approach 3

[0065] Specific embodiment three: assign a value to the material attribute at the initial moment in the callus, and assign the material attribute at the initial moment in the callus to the material attribute value of the granulation tissue;

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a fracture healing simulation method based on a tissue oxygen environment and a mechanical environment. The method comprises the steps of establishing a three-dimensional geometric model of a fracture part, meshing the obtained geometric model to establish a finite element model of a bone and a callus, analyzing and solving the finite element model to calculate a partial strain of a fracture area, establishing a vascular growth model of the fracture area according to force stimulation, establishing each cell proliferation and differentiation model of the fracture area,establishing an oxygen transport model of the fracture area, calculating a new material attribute in a tissue, establishing a fracture healing iteration simulation process of a force biological adjustment algorithm, and judging whether the material attribute in the tissue reaches a material attribute value of the bone or not according to the calculated tissue material attribute value, completing simulation if so, otherwise updating the tissue material attribute value and entering into next iteration simulation.

Description

technical field [0001] The invention relates to the field of biomedical engineering, in particular to a fracture healing simulation method based on tissue oxygen environment and mechanical environment. Background technique [0002] With the development of transportation, construction and other industries and the intensification of population aging, the number of patients with traffic injuries, construction injuries and elderly osteoporotic fractures has increased rapidly. According to the statistics of traffic accidents in 2015, a total of 10,597,358 car accidents occurred in 2015, 98.5% of whom were injured; according to the big data on the health of the elderly in China in 2015, osteoporosis has leapt to the No. 1 common disease and frequently-occurring disease. seven. The prevalence rate of people over 60 years old is 56%, and the incidence rate of women is 60%-70%. Among them, the incidence of fracture is close to one-third, and the annual medical expenses need RMB 15 ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G16H50/50
Inventor 王沫楠王新宇杨宁
Owner HARBIN UNIV OF SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com