A method for trichothecene detoxification

A technology of trichothecenes and terpenes, which is used in the molding or processing of animal feed, food science, climate change adaptation, etc., and can solve the problems of insufficient preventive measures and unrealistic feasibility.

Inactive Publication Date: 2017-06-20
VETERINRINSTTET
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because preventative measures to prevent the production of trichothecenes are insufficient or practical, it is desirable to find methods that can detoxify samples such as produce before they reach consumers

Method used

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  • A method for trichothecene detoxification
  • A method for trichothecene detoxification
  • A method for trichothecene detoxification

Examples

Experimental program
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Embodiment Construction

[0072] This document relates to the detoxification of trichothecenes (eg, type A, type B, type C and / or type D trichothecenes). Although the methods or uses described herein may refer only to the detoxification of Type A and / or Type B trichothecenes, it is understood that the methods or uses described herein may be used for Type A, Type B, Type C and / or Trichothecenes D-type trichothecenes. In particular, the present document relates to a method for the detoxification of samples, such as grain-derived or grain-containing samples, contaminated with trichothecenes, such as with type A and / or type B trichothecenes, wherein The method comprises the step of reacting a sample contaminated with trichothecenes type A and / or type B with a thiol-containing compound under acidic, neutral or alkaline conditions. Acidic, neutral or basic conditions can be provided by an aqueous solution having an acidic, neutral or basic pH. The pH in the aqueous solution or reaction mixture can be chose...

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Abstract

The present document is directed to detoxification of trichothecenes using a method involving trichothecene epoxide ring opening. In particular, the present document discloses the detoxification of a trichothecene by reaction with a thiol containing compound under conditions where the pH is equal to or higher than one pH unit less than the pKa of a thiol group of the thiol containing compound.

Description

technical field [0001] The present document relates to the detoxification of samples contaminated with trichothecenes, eg, samples contaminated with type A and / or type B trichothecenes. More specifically, the present document relates to a method for detoxifying a sample contaminated with trichothecenes (eg, type A and / or type B trichothecenes) by reaction with thiols under alkaline conditions. Background technique [0002] Trichothecenes are a large family of chemically related mycotoxins that are generally toxic to humans, animals, plants and eukaryotic cells. Trichothecenes can be produced by, for example, Fusarium, Myrothecium, Trichoderma, Trichothecium, Cephalosporium ( Produced by fungi and molds such as Cephalosporium, Verticimonosporium and Stachybotrys. For example, when trichothecenes are present in food or agricultural products, they cause serious health problems in humans and animals. Toxicity varies according to the specific trichothecene mycotoxin, but commo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K40/00A23K10/30A23K20/10A23K50/10A23K50/80A23L5/20
CPCA23K40/00A23K10/30A23K20/10A23K50/10A23K50/80Y02A40/818A23L5/27A23V2002/00
Inventor A·斯坦尼奇S·乌利希C·O·迈尔斯
Owner VETERINRINSTTET
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