Sers active liquid droplet, preparation method and molecular detection method

An active liquid and droplet technology, which is applied in the fields of analyzing materials, measuring devices, material excitation analysis, etc., can solve the problems such as the difficulty of precise laser focusing, and achieve the effects of strong controllability, wide application range and improved convenience.

Active Publication Date: 2019-06-14
北京芯创睿胜科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the liquid has a certain height, and its contour changes in a specific arc, so it is difficult to accurately focus the laser

Method used

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  • Sers active liquid droplet, preparation method and molecular detection method
  • Sers active liquid droplet, preparation method and molecular detection method
  • Sers active liquid droplet, preparation method and molecular detection method

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Embodiment Construction

[0034] The present invention will be further described below in conjunction with specific drawings and embodiments.

[0035] In order to avoid the harsh requirements on focusing in the existing SERS molecular detection and reduce the operational difficulty of the molecular detection process, the present invention includes liquid droplets and a number of metal nanocomposite particles 8 with SERS activity enriched by the liquid droplets, The metal nanocomposite particles 8 with SERS activity are located in the droplet or attached to the surface of the droplet; the metal nanocomposite particles 8 with SERS activity include the metal nanoparticle body 5 .

[0036] Specifically, the droplet includes water droplet, oil droplet, or solution droplet using water or oil as a solvent. The metal nano-loaded particle 8 with SERS activity is located in the droplet body or attached to the surface of the droplet body, and the metal nanocomposite particle 8 with SERS activity includes a metal ...

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Abstract

The invention relates to an SERS (surface enhanced Raman scattering) active droplet and a preparation method and molecular detection method thereof, in particular to an SERS active droplet based on candle ash nanoparticle structure, a preparation method of the SERS active droplet, and a molecular detection method using the SERS active droplet, and belongs to the technical field of SERS detection. The SERS active droplet according to the technical scheme provided herein comprises a droplet body and a plurality of SERS active metal composite nanoparticles enriched thereby, the SERS active metal composite nanoparticles are positioned in the droplet body or adhered to the surface of the droplet body; each of the SERS active metal composite nanoparticles includes a metal nanoparticle body. The ability to absorb and enrich gold nanoparticles can be achieved herein, the strict requirement of existing SERS molecular detection for focusing can be avoided, transferring is facilitated, test convenience is improved, the preparation process is simple, and the SERS droplet is highly controllable, widely applicable and good in safety and reliability.

Description

technical field [0001] The present invention relates to an active liquid droplet and a molecular detection method utilizing the active liquid droplet, in particular to a SERS active liquid droplet, a preparation method and a molecular detection method, specifically a SERS active liquid based on a candle ash nanoparticle structure The preparation method of droplet, SERS active droplet and the molecular detection method using said SERS active droplet belong to the technical field of SERS detection. Background technique [0002] The detection technology of Raman scattering spectroscopy is a method of material structure analysis that does not require labeling of the sample to be detected, and has the characteristics of non-destructive and contact-free. With the development of laser technology and weak signal detection and reception technology, as a means to realize the molecular level detection of material structure, Raman scattering spectroscopy detection technology is expected...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/65B82Y30/00B82Y15/00
CPCB82Y15/00B82Y30/00G01N21/658
Inventor 赵柱毛海央
Owner 北京芯创睿胜科技有限公司
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