Rat endotracheal intubation method and application

Abstract

The invention discloses a rat endotracheal intubation method and application. The method mainly comprises the following steps that an anesthetic rat is placed on the back and fixed, the upper and lower jaws of the rat are opened, the rat's glottis is exposed by means of a laryngoscope, and a tracheal tube, which is 6 to 7cm long, is directly inserted into the trachea, namely the opening and closing part of the glottis, by means of the observation of the laryngoscope; a thin steel wire is inserted into the tracheal tube and a small section of water column is inected; the water column movement change in the tracheal tube is observed, if the water column doesn't move or is sprayed out or sucked in violently, it means that the tracheal tube is enters the esophagus, and intubation is needed again; if the water column in the tracheal tube moves up and down rhythmically along with the animal's breathing frequency, it means that the tracheal tube is inserted into the trachea. The method is used for endotracheal intubation under the conditions of rat trachea administration, rat administration and molding, and rat pulmonary function detection and the like, and the method has the advantages of being simple, speedy, free of injuries, high in molding and administration success rate, accurate in pulmonary function detection and the like.

Description

technical field [0001] The invention belongs to the technical field of tracheal intubation, in particular to a rat tracheal intubation method and its application. Background technique [0002] The rat tracheal intubation technique is commonly used in rat tracheal drug delivery, rat tracheal drug delivery modeling, rat pulmonary function measurement, and experimental research related to respiratory diseases. Tracheal intubation is required for rat-related model replication and rat lung function testing. The tracheal intubation technique directly affects the success rate of model replication and lung function testing, and is critical throughout the experiment. [0003] In the past, the methods of tracheal intubation were mostly blind intubation and tracheotomy. [0004] The blind insertion method is easy to insert into the esophagus, the success rate is low, and repeated trial insertion is required. It is easy to damage the pharynx of the rat, resulting in the secretion of a ...

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a rat tracheal intubation method, aiming to solve the problems of injury, trauma and error in experimental results to rats in the existing tracheal intubation method