Medical hyaluronic acid bioremediation plaster and preparation method thereof

Abstract

The invention discloses a medical hyaluronic acid bioremediation plaster and a preparation method thereof; a hyaluronic acid raw liquid in the bioremediation plaster comprises the following components by the mass percentage: 0.001%-0.3% of a higher-molecular-weight hyaluronic acid, 0.001%-0.1% of a medium-molecular-weight hyaluronic acid, 0.001%-0.3% of an enzyme-digestion oligomeric hyaluronic acid, 0.01%-5% of butanediol, 1%-15% of glycerin, 0.001%-0.2% of dragosantol, 0.01%-1.5% of allantoin, 0.1%-0.8% of carbomer 980, 0.01%-0.6% of D-panthenol, 0.02%-1% of sodium hydroxide, 0.05%-5% of an aloe extract, 0.05%-3% of a licorice root extract, 0.001%-0.5% of methylparaben, and the balance purified water. The medical hyaluronic acid bioremediation plaster takes non-woven cloth or silk cloth as a substrate. The medical hyaluronic acid bioremediation plaster prepared from the hyaluronic acids with the high molecular weight, medium molecular weight and oligomeric molecular weight is applied in remediation and nursing of facial acne, eczematous dermatitis, and laser and photon rejuvenation postoperation, promotes wound surface healing, and achieves the effects of remediation and reconstruction of a skin barrier function.

Description

technical field [0001] The invention relates to the field of medical repair, in particular to a medical hyaluronic acid biological repair patch and a preparation method thereof. Background technique [0002] Hyaluronic acid (Hyaluronic Acid, HA) is a linear polysaccharide composed of β-1,3-glucosylacetamide (β-1,3-N-acetylglucosamine) and β-1,4-gluconic acid (β-1, 4-glucuronic acid) is a repeating disaccharide unit formed by β-1,4 glycosidic bonds, and this disaccharide repeating unit is repeatedly connected by β-1,3 glycosidic bonds to form a linear polymer. Hyaluronic acid can absorb water more than 500 times its own molecular weight, and can also affect cell transfer, differentiation, growth, blood vessel transfer, immune regulation, and free radical scavenging. In addition, hyaluronic acid has no species difference, has extremely excellent biocompatibility and biodegradability, and is widely used in medicine and skin care products. [0003] The skin is an important res...

AI Technical Summary

Problems solved by technology

At present, most of the products on the market are made of hyaluronic acid with a single molecular weight or arbitrarily mixed with several hyaluronic acids with different molecular weights, which cannot maximize the barrier protection and repair effect of hyaluronic acid on the skin.

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