Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A screening method for individualized medicine and its application

A drug and drug screening technology, applied in the field of biomedicine, can solve problems that affect individualized drug screening and hinder the development of new individualized drugs, achieve high commercial prospects and practical significance, improve objectivity, and strong practicability

Active Publication Date: 2018-07-17
PROTEINT (TIANJIN) BIOTECHNOLOGY CO LTD
View PDF9 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The reason why precision medicine is "precise" is that its treatment plan caters to the patient's individual cause of disease, that is, "prescribes the right medicine": while the current precision medicine attempt based on gene sequencing, due to (as mentioned above) the one-sidedness of gene sequencing in the analysis of pathogenic factors, only It is a one-sided "prescribe the right medicine", which will seriously affect the screening of individualized drugs and hinder the development of new individualized drugs

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A screening method for individualized medicine and its application
  • A screening method for individualized medicine and its application
  • A screening method for individualized medicine and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0064] The present invention will be further described below in conjunction with the accompanying drawings.

[0065] A method for screening and verifying individualized medicines, comprising the following steps:

[0066] (1) Construction of disease-related pathogenic protein molecular database: use LC / MS / MS to detect the pathological tissue samples of a certain diseased population and the corresponding tissue samples of the non-diseased population, and compare and analyze the diseased population and the non-diseased population Identify the different protein molecules between the affected population and the non-affected population as the molecular pathogenic factors of the disease, and establish a database of pathogenic protein molecules related to the disease;

[0067] (2) Establishment of the correlation database of patients' individualized clinical course symptoms-protein pathogenic factors response characteristics: analyze the inter-individual differences in the characteris...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a screening method of individualized medicine. The method includes: building a disease-related pathogenic protein molecule database, building a paint individual clinical disease course symptom-protein pathogenic factor response feature relevance database, building a disease model target medicine-protein response relevance database, and acquiring a medicine screen result. The screening method has the advantages that the method is brand new and pioneering and used for individualized precise medical treatment, genetic and environment pathogenic factors and patient disease course features can be accurately and comprehensively reflected in the detecting and analyzing result of protein molecules, and objective, precise and individualized treatment medicine applicable to different patient disease course features is screened according to the target medicine's correction of the pathogenic protein molecules.

Description

technical field [0001] The invention belongs to the field of biomedicine, and particularly relates to a drug screening method based on protein analysis, and also relates to the method to establish a one-to-one correspondence between different disease characteristics of different patients and different drugs, so that the development and use of new individualized drugs can be based on evidence. Keyi promotes precision medicine. Background technique [0002] The basis of precision medicine is individualized etiology analysis: precision medicine is to accurately measure and interpret various individualized pathogenic factors (genetic and environmental) of patients, reflect them at the molecular level, and then formulate individualized molecular pathogenic factors. The factor is targeted and individualized treatment. [0003] The best analysis method for individualized molecular pathogenic factors is protein analysis: the essence of precision medicine is to collect and analyze t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N30/88
CPCG01N30/88
Inventor 李捷
Owner PROTEINT (TIANJIN) BIOTECHNOLOGY CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com