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Composition for promoting hair growth or preventing hair loss

A hair loss and hair growth technology, applied in hair care, drug combination, cosmetic preparations, etc., can solve problems such as unpredictable, sticky skin, sexual dysfunction, etc., to relieve inflammation, prevent hair loss, Excellent hair growth effect

Inactive Publication Date: 2016-09-28
NEOPHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] However, it has been reported that minoxidil has a viscous feeling of use and a side effect of skin-induced irritation, and that finasteride is currently used in an oral formulation, but it is reported that taking This preparation will be accompanied by side effects such as sexual dysfunction, and it needs to be taken for a long time to produce an effect on hair loss. For these 5α-reductase activity inhibitors, it is difficult to expect the effect produced by coating, and it can only be expected to be brought by oral administration. to the effect, so there is a lot of inconvenience in use

Method used

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  • Composition for promoting hair growth or preventing hair loss
  • Composition for promoting hair growth or preventing hair loss
  • Composition for promoting hair growth or preventing hair loss

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] A hair growth composition was prepared by mixing 5% by weight of oleoylethanolamine, 30% by weight of ethanol, 50% by weight of polypropylene glycol (Mw=76.09) and 15% by weight of water prepared by the method.

[0046] Evaluation was carried out by in vivo experiments mainly using C57BL / 6 mice six weeks after birth (place of purchase, China) for hair growth and hair growth effects. The C57BL / 6 mouse is an animal model most widely used as a hair growth experiment with a specific cycle in which the hair is in the catagen phase from the age of six weeks after birth, and the hair is in the catagen phase from the age of seven weeks. The telogen phase returns to the growth phase at 12 weeks of age.

[0047] Let the mice go through a one-week adaptation period under the feeding conditions of 23° C., 55% relative humidity, and 12 hours of lighting time, and then conduct the experiment at the age of 7 weeks.

[0048] After placing the mouse in a desiccator filled with ether an...

Embodiment 2

[0064] [Example 2] Evaluation of Relief of Inflammation

[0065] Purchase female Balb / C mice six weeks after birth (place of purchase, China), and under the feeding conditions of 23°C, relative humidity of 55%, and lighting time of 12 hours, after a week of adaptation period, to 7 weeks 20 μl of 12-O-tetradecanoylphorbol-13-acetate (TPA), which is an oncogenic promoter, was applied to the right ear of the mouse at a concentration of 50 μg / mL.

[0066] After 10 minutes, 20 μl of the hair growth composition of Example 1 was applied to the experimental group respectively. After 6 hours, the ear was cut off with a 6 mm punch, and the weight was measured.

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PUM

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Abstract

The present invention relates to a composition for promoting hair growth, preventing hair loss, or relieving inflammation and, more specifically, to a composition which has excellent stability to the skin, has no side effects, and exhibits excellent effects of hair growth promotion and hair loss prevention by promoting hair growth and delaying hair loss. The composition according to the present invention contains a material belonging to a ceramidase inhibitor, glycol, C1-C5 lower alcohol, and water, and thus the composition is safe, has no side effects, can be continuously used for a long period of time, has an excellent effect of hair growth promotion or hair loss prevention by significantly promoting hair growth, and exhibits an inflammation relieving effect as well as a hair growth promoting effect, additionally.

Description

technical field [0001] The present invention relates to a composition for promoting hair growth, preventing hair loss or relieving inflammation, and in more detail, relates to a composition that has excellent stability to the skin, has no side effects, and promotes hair growth and delays hair loss, thereby promoting hair growth. A composition excellent in hair growth and hair fall prevention effects. Background technique [0002] The most common cause of hair loss is heredity, but recently, the number of people who lose hair is increasing due to social pressure, environmental pollution, westernized eating habits such as instant food, frequent perms and hair dyes, and wrong scalp care. . [0003] Hair grows and falls out repeatedly through a cycle of anagen (Anagen), catagen (Catagen), and telogen (Telogen), thereby maintaining hair. In detail, it can be divided into anagen (anagen), catagen (catagen), telogen (telogen) and neonatal period. The anagen is the period when the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/41A61K8/33A61K8/30A61Q7/00A61Q5/00
CPCA61Q7/00A61Q19/00A61K8/86A61K2800/782A61K8/42A61P17/14A61K31/164A61K8/34A61K31/16A61K47/10A61K2800/75A61Q19/08
Inventor 停世规配钟焕朴部万
Owner NEOPHARM CO LTD
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