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Fractured end micro-movement and blood supply based fracture healing simulation system

A fracture healing and simulation system technology, applied in the field of biomedical engineering, can solve the problems of limited number of experiments and experimental species, and the mechanism of blood's influence on fracture healing is not clear, so as to reduce delayed union, reduce fracture nonunion, and improve surgical success. rate effect

Inactive Publication Date: 2016-05-04
HARBIN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] 3. The mechanism of the effect of blood on fracture healing is not yet clear;
[0008] 4. Most clinical trials are in vivo experiments, so the number of experiments and experimental species will be limited

Method used

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  • Fractured end micro-movement and blood supply based fracture healing simulation system
  • Fractured end micro-movement and blood supply based fracture healing simulation system
  • Fractured end micro-movement and blood supply based fracture healing simulation system

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Experimental program
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specific Embodiment approach 1

[0029] Specific implementation mode one: as figure 1 As shown, a fracture healing simulation system based on stump micro-motion and blood supply in this embodiment includes: fracture healing simulation system software 1 , input device 2 , and display device 3 .

[0030] The fracture healing simulation system software 1 includes: a geometric modeling module, a grid division module, an environment initialization module, a biomechanical calculation module, and a biological environment module.

[0031] The geometric modeling module is used to carry out the establishment of the three-dimensional surface model of the callus at the fracture place after image preprocessing according to the imported two-dimensional tomographic image data (such as CT image);

[0032] The grid division module is used for surface grid division of a three-dimensional surface model; and for generating a volume grid model from the surface grid model to realize the discretization of a continuous three-dimensi...

specific Embodiment approach 2

[0040] Specific implementation mode two, such as figure 2 As shown, in the present embodiment, the concrete process of the described fracture healing simulation system software 1 realizing its function is:

[0041] 1) Geometric modeling module

[0042] like image 3 As shown, the geometric modeling module includes the steps of threshold screening, interactive segmentation, and 3D reconstruction: through the steps of threshold screening, interactive segmentation, and 3D reconstruction, the 3D geometric modeling of callus is realized; through the process of threshold screening, the patient's bone Cartilage, muscle, cartilage, fat, skin and other tissues are initially segmented; the quality and speed of image segmentation can be improved by manually erasing and repairing a single image through the interactive segmentation process; through the process of 3D reconstruction, the 2D tomographic image can be 3D surface model is generated from the region segmented in ; as can be see...

Embodiment

[0087] In order to better illustrate the method and its significance, an example is given below to illustrate the operation process of the present invention.

[0088] Simulate the tibial fracture healing process:

[0089] 1) Get image data

[0090] In order to establish a three-dimensional geometric model of the callus at the patient's fracture site, CT and MRI scans of the tissue at the patient's fracture site are required to obtain the DICOM data format and collect the data.

[0091] 2) Establish a three-dimensional geometric model of the callus at the fracture site and input patient information

[0092] Import the CT and MRI images in DICOM format into the fracture healing simulation system software through the computer USB interface, and then input the patient's name, gender, age, case, diagnosis and examination results and other information into the operation interface. After performing a threshold screening operation on the image, target tissues such as bone, muscle, f...

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Abstract

The invention provides a fractured end micro-movement and blood supply based fracture healing simulation system, relating to the field of biomedical engineering. The system is used for predicting a complicated process of fracture healing and exploring undetermined mechanisms in fracture healing. The system comprises a fracture healing simulation sub-system, an input module and a display module. The fracture healing simulation sub-system (1) comprises a geometry modeling module, a grid partition module, an environment initialization module, a biomechanical calculation module and a biological environment module. The biological environment module is used for creating a biochemical environment of callus in fracture healing so as to finish tissue differentiation in the callus. According to the system, blood supply is used as a dynamic variable and is introduced to the fracture healing simulation system, so that the fracture healing process can be simulated more accurately. The system can perform experiment simulation repeatedly, thereby helping to find out the best fractured end micro-movement value and the impact of blood on fracture healing.

Description

technical field [0001] The invention relates to the field of biomedical engineering, in particular to a fracture healing simulation system based on micro-motion and blood supply of broken ends. Background technique [0002] The musculoskeletal system plays an important role in the human body, and its main functions include: motor function, protective function, support function, hematopoietic function, and storage function. In the statistical data of common diseases that endanger people's health in our country, trauma has risen from the 9th in the early days of the founding of the People's Republic of China to the 4th in recent years with the development of industry and transportation. Fracture is a common trauma. The high incidence of fracture makes the study of fracture mechanism and promotion of healing particularly urgent. Once a fracture occurs, unlike other tissue damage repairs, the fracture is not connected by fibrous connective tissue, but by bone tissue. Fully rege...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F17/50G06T17/30
CPCG06F30/23G06T17/30
Inventor 王沫楠杨宁
Owner HARBIN UNIV OF SCI & TECH
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